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1/15/2026 8:12:50 AM | Browse: 1 | Download: 1
Publication Name World Journal of Cardiology
Manuscript ID 112541
Country India
Received
2025-07-31 02:06
Peer-Review Started
2025-07-31 02:06
First Decision by Editorial Office Director
2025-08-22 09:22
Return for Revision
2025-08-22 09:22
Revised
2025-09-01 16:07
Publication Fee Transferred
Second Decision by Editor
2025-11-20 23:18
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-21 05:48
Articles in Press
2025-11-21 05:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-08 01:27
Publish the Manuscript Online
2026-01-15 08:12
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Observational Study
Article Title Pulmonary hypertension in patients with obstructive sleep apnea: Correlation with disease severity and quality of life
Manuscript Source Invited Manuscript
All Author List Praveen Kumar, Ajay Kumar Verma, Jyoti Bajpai, Sujita Kumar Kar, Akshyaya Pradhan, Surya Kant, Rajiv Garg, Santosh Kumar, Ram Avadh Singh Kushwaha, Sanjeev Kumar Verma, Darshan Kumar Bajaj, Anand Srivastava and Ankit katiyar
ORCID
Author(s) ORCID Number
Ajay Kumar Verma http://orcid.org/0000-0002-2973-1793
Jyoti Bajpai http://orcid.org/0000-0001-6337-856X
Sujita Kumar Kar http://orcid.org/0000-0003-1107-3021
Akshyaya Pradhan http://orcid.org/0000-0002-2360-7580
Surya Kant http://orcid.org/0000-0001-7520-5404
Funding Agency and Grant Number
Corresponding Author Jyoti Bajpai, Associate Professor, FCCP, MD, Department of Respiratory Medicine, King George’s Medical University, Shahmina Road, Chowk, Lucknow 226003, Uttar Pradesh, India. jyotibajpai33@gmail.com
Key Words Apnea-hypopnea index; Obstructive sleep apnea; Pulmonary hypertension; Quality of life; World Health Organisation Quality of Life Brief Version
Core Tip Obstructive sleep apnea (OSA) is increasingly recognized as a contributor to cardiovascular morbidity, including pulmonary hypertension (PH). This present cross sectional study aimed to assess the prevalence and severity of PH in newly diagnosed OSA patients. Further, it evaluated its association with disease severity as well as quality of life (QoL). The 113 patients with de novo diagnosis with OSA underwent echocardiography to assess pulmonary artery pressures and completed the World Health Organisation Quality of Life Brief Version (WHOQOL-BREF) questionnaire. The prevalence of PH in patients with OSA was 71.68% and the prevalence increased with age and OSA severity (P < 0.01). There was positive correlation between apnea-hypopnea index and oxygen desaturation index with right ventricular systolic pressure (r = 0.677) and mean pulmonary artery pressure (r = 0.543). WHOQOL-BREF scores were significantly lower in PH patients, particularly in physical and psychological domains. PH is a prevalent and underdiagnosed complication of OSA that negatively impacts QoL. There is imminent need for integration of echocardiographic screening and QoL assessments into the routine management of OSA.
Publish Date 2026-01-15 08:12
Citation

Kumar P, Verma AK, Bajpai J, Kar SK, Pradhan A, Kant S, Garg R, Kumar S, Kushwaha RAS, Verma SK, Bajaj DK, Srivastava A, katiyar A. Pulmonary hypertension in patients with obstructive sleep apnea: Correlation with disease severity and quality of life. World J Cardiol 2026; 18(1): 112541

URL https://www.wjgnet.com/1949-8462/full/v18/i1/112541.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i1.112541
Full Article (PDF) WJC-18-112541-with-cover.pdf
STROBE Statement 112541-STROBE-statement.pdf
Manuscript File 112541_Auto_Edited_061015.docx
Answering Reviewers 112541-answering-reviewers.pdf
Audio Core Tip 112541-audio.m4a
Biostatistics Review Certificate 112541-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 112541-conflict-of-interest-statement.pdf
Copyright License Agreement 112541-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 112541-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 112541-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 112541-non-native-speakers.pdf
Peer-review Report 112541-peer-reviews.pdf
Scientific Misconduct Check 112541-scientific-misconduct-check.png
Scientific Editor Work List 112541-scientific-editor-work-list.pdf
CrossCheck Report 112541-crosscheck-report.pdf