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5/20/2026 8:22:30 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 112559
Country China
Received
2025-12-05 08:36
Peer-Review Started
2025-12-05 08:36
First Decision by Editorial Office Director
2025-12-25 08:52
Return for Revision
2025-12-25 08:52
Revised
2026-01-20 08:21
Publication Fee Transferred
Second Decision by Editor
2026-02-25 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-25 07:44
Articles in Press
2026-02-25 07:44
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-13 01:05
Publish the Manuscript Online
2026-05-20 08:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Construction and efficacy validation of a multi-parametric contrast-enhanced ultrasound nomogram model for discriminating hepatic inflammatory lesions from malignancies
Manuscript Source Unsolicited Manuscript
All Author List Si-Jie Mou, San-Mei Yu, Yan-Ni Xiang and Bo Tang
ORCID
Author(s) ORCID Number
Bo Tang http://orcid.org/0009-0000-1509-3797
Funding Agency and Grant Number
Corresponding Author Bo Tang, Ultrasound Department, Taizhou First People's Hospital, No. 218 Hengjie Road, Huangyan District, Taizhou 318020, Zhejiang Province, China. tangbo19852025@163.com
Key Words Hepatic; Contrast-enhanced ultrasound; Machine learning; Differential diagnosis; SHapley Additive exPlanations; Inflammatory lesions; Malignant tumors
Core Tip We developed and externally tested (within an independent test set) a multi-parametric contrast-enhanced ultrasound-based, SHapley Additive exPlanations-interpretable machine learning nomogram to differentiate hepatic inflammatory lesions from malignant tumors. Logistic regression showed the best overall generalization (area under the curve = 0.965; accuracy = 94.35%) and significantly outperformed alpha-fetoprotein and Model for End-Stage Liver Disease scores. Blood flow signals and wash-in time, as the key driving factors of model decision-making, can offer an intuitive and clinically relevant diagnostic reference basis.
Publish Date 2026-05-20 08:22
Citation

Mou SJ, Yu SM, Xiang YN, Tang B. Construction and efficacy validation of a multi-parametric contrast-enhanced ultrasound nomogram model for discriminating hepatic inflammatory lesions from malignancies. World J Gastroenterol 2026; 32(20): 112559

URL https://www.wjgnet.com/1007-9327/full/v32/i20/112559.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i20.112559
Full Article (PDF) WJG-32-112559-with-cover.pdf
Manuscript File 112559_Auto_Edited_015253.docx
Answering Reviewers 112559-answering-reviewers.pdf
Audio Core Tip 112559-audio.mp3
Biostatistics Review Certificate 112559-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 112559-conflict-of-interest-statement.pdf
Copyright License Agreement 112559-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 112559-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 112559-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 112559-non-native-speakers.pdf
Supplementary Material 112559-supplementary-material.pdf
Peer-review Report 112559-peer-reviews.pdf
Scientific Misconduct Check 112559-scientific-misconduct-check.png
Scientific Editor Work List 112559-scientific-editor-work-list.pdf
CrossCheck Report 112559-crosscheck-report.pdf