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2/11/2026 3:41:43 AM | Browse: 2 | Download: 12
Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 112588
Country India
Received
2025-08-04 06:34
Peer-Review Started
2025-08-04 06:34
First Decision by Editorial Office Director
2025-08-28 09:28
Return for Revision
2025-08-28 09:28
Revised
2025-09-26 13:27
Publication Fee Transferred
Second Decision by Editor
2025-12-12 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-12 07:39
Articles in Press
2025-12-12 07:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-03 06:32
Publish the Manuscript Online
2026-02-11 03:41
ISSN 2150-5349 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Liver clock: Malalignment and entrainment therapeutics
Manuscript Source Invited Manuscript
All Author List Shaiphali Sharma, Shreya Pandey and Ajay Kumar Mishra
ORCID
Author(s) ORCID Number
Ajay Kumar Mishra http://orcid.org/0000-0001-9619-0766
Funding Agency and Grant Number
Corresponding Author Ajay Kumar Mishra, Assistant Professor, Department of Hepatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raibareilly Road,, Lucknow 226014, Uttar Pradesh, India. ajaymishrapandit@gmail.com
Key Words Circadian rhythm; Liver clock; Metabolic dysfunction-associated steatotic liver disease; Suprachiasmatic nucleus; Clock gene; Melatonin; Life style disorders
Core Tip Liver clock is peripheral clock of hepatocytes concerned with metabolic genes and functions. It is desynchronised to central clock in metabolic and life style disorders. It can be resynchronised by various life style and therapeutic measures including modifying eating behaviours, light exposure, excercise or activity modification. This mini-review discusses causes of misalignment of liver clock and how to fix them.
Publish Date 2026-02-11 03:41
Citation

Sharma S, Pandey S, Mishra AK. Liver clock: Malalignment and entrainment therapeutics. World J Gastrointest Pharmacol Ther 2026; 17(1): 112588

URL https://www.wjgnet.com/2150-5349/full/v17/i1/112588.htm
DOI https://dx.doi.org/10.4292/wjgpt.v17.i1.112588
Full Article (PDF) WJGPT-17-112588-with-cover.pdf
Manuscript File 112588_Auto_Edited_061257.docx
Answering Reviewers 112588-answering-reviewers.pdf
Audio Core Tip 112588-audio.m4a
Conflict-of-Interest Disclosure Form 112588-conflict-of-interest-statement.pdf
Copyright License Agreement 112588-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 112588-non-native-speakers.pdf
Peer-review Report 112588-peer-reviews.pdf
Scientific Misconduct Check 112588-scientific-misconduct-check.png
Scientific Editor Work List 112588-scientific-editor-work-list.pdf
CrossCheck Report 112588-crosscheck-report.pdf