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1/14/2026 8:09:12 AM | Browse: 1 | Download: 16
Publication Name World Journal of Diabetes
Manuscript ID 112621
Country China
Received
2025-08-01 03:32
Peer-Review Started
2025-08-05 00:11
First Decision by Editorial Office Director
2025-09-02 03:26
Return for Revision
2025-09-02 03:26
Revised
2025-09-13 15:37
Publication Fee Transferred
2025-09-30 02:25
Second Decision by Editor
2025-11-28 03:02
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-28 10:24
Articles in Press
2025-11-28 10:24
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-31 05:10
Publish the Manuscript Online
2026-01-14 08:09
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Retrospective Study
Article Title Combined assessment with stress hyperglycemia ratio and time in range: Associations with twenty-eight-day mortality in surgical intensive care unit patients
Manuscript Source Unsolicited Manuscript
All Author List Shuang Liu, Bai-Ge Cao, Yue Ma, Jin-Fang Xu, Quan-Hong Zhou and Cong-Rong Wang
ORCID
Author(s) ORCID Number
Bai-Ge Cao http://orcid.org/0000-0002-7360-015X
Jin-Fang Xu http://orcid.org/0000-0002-1827-8145
Cong-Rong Wang http://orcid.org/0000-0002-8645-1114
Funding Agency and Grant Number
Funding Agency Grant Number
Shanghai Science and Technology Development Funds 22410713200
The Noncommunicable Chronic Diseases-National Science and Technology Major Project 2023ZD0509206
National Natural Science Foundation of China 82471893
Key Discipline Project of Hongkou District Health Commission HKLCFC202403
Research fund from Shanghai Fourth People’s Hospital sykyqd01801
Research fund from Shanghai Fourth People’s Hospital SY-XKZT-2021-1001
Corresponding Author Cong-Rong Wang, PhD, Professor, Department of Endocrinology and Metabolism, Shanghai Fourth People’s Hospital Affiliated to Tongji University, No. 1279 Sanmen Road, Shanghai 200434, China. crwang@tongji.edu.cn
Key Words Surgical intensive care unit; Stress hyperglycemia ratio; Time in range; Twenty-eight-day mortality; Hyperglycemia
Core Tip While the stress hyperglycemia ratio (SHR) has been widely examined as a marker of acute glycemic disturbance, prior studies have largely emphasized its independent prognostic value, often neglecting its interaction with longitudinal glycemic control indicators. In this study, we evaluated the combined effect of SHR and time in range (TIR) on 28-day mortality in surgical ICU patients. We found that patients with both elevated SHR and reduced TIR exhibited the highest risk of death, with a 2.37-fold increase compared to those with low SHR and high TIR. These findings highlight the prognostic relevance of both acute hyperglycemia and persistent glycemic dysregulation, and emphasize the potential value of integrated glucose management strategies in critically ill patients.
Publish Date 2026-01-14 08:09
Citation

Liu S, Cao BG, Ma Y, Xu JF, Zhou QH, Wang CR. Combined assessment with stress hyperglycemia ratio and time in range: Associations with twenty-eight-day mortality in surgical intensive care unit patients. World J Diabetes 2026; 17(1): 112621

URL https://www.wjgnet.com/1948-9358/full/v17/i1/112621.htm
DOI https://dx.doi.org/10.4239/wjd.v17.i1.112621
Full Article (PDF) WJD-17-112621-with-cover.pdf
Manuscript File 112621_Auto_Edited_081710.docx
Answering Reviewers 112621-answering-reviewers.pdf
Audio Core Tip 112621-audio.m4a
Biostatistics Review Certificate 112621-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 112621-conflict-of-interest-statement.pdf
Copyright License Agreement 112621-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 112621-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 112621-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 112621-non-native-speakers.pdf
Supplementary Material 112621-supplementary-material.pdf
Peer-review Report 112621-peer-reviews.pdf
Scientific Misconduct Check 112621-scientific-misconduct-check.png
Scientific Editor Work List 112621-scientific-editor-work-list.pdf
CrossCheck Report 112621-crosscheck-report.pdf