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Articles Published Processes
4/23/2026 11:05:47 AM | Browse: 0 | Download: 0
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Received |
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2025-08-04 08:31 |
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Peer-Review Started |
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2025-08-04 08:31 |
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First Decision by Editorial Office Director |
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2025-08-14 03:05 |
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Return for Revision |
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2025-08-14 08:52 |
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Revised |
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2025-08-22 16:09 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-09 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-09 13:52 |
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Articles in Press |
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2026-01-09 13:52 |
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Edit the Manuscript by Language Editor |
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2026-01-15 00:21 |
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Typeset the Manuscript |
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2026-03-29 03:10 |
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Publish the Manuscript Online |
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2026-04-23 11:05 |
| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Clinical Trial |
| Article Title |
Open-label randomized controlled study of salt-restricted vs salt-unrestricted diet in cirrhosis patients with hyponatremia
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sudheer Marrapu, Ramesh Kumar, Divendu Bhushan, Sudhir Kumar, Abhishek Kumar, Rajeev N Priyadarshi and Utpal Anand |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ramesh Kumar, Additional Professor, DM, Head, Department of Gastroenterology, All India Institute of Medical Sciences, Patna 801507, Bihar, India. docrameshkr@gmail.com |
| Key Words |
Dietary salt; Sodium restriction; Cirrhosis; Hyponatremia; Acute kidney injury; Nutrition; Sarcopenia |
| Core Tip |
This study highlights the potential harm of salt restriction in cirrhotic patients with moderate to severe hyponatremia. Patients in the salt-restricted diet group (5 g/day) had a significantly higher risk of acute kidney injury, poorer nutritional and hemodynamic profiles, and increased short-term mortality compared to those in the salt-unrestricted diet group (10 g/day). Importantly, no significant improvement in ascites control was observed with salt restriction. These results question the routine use of salt restriction in this subgroup and emphasize the need for a more tailored dietary approach to optimize renal function, nutrition, and survival outcomes in hyponatremic cirrhotic patients. |
| Publish Date |
2026-04-23 11:05 |
| Citation |
Marrapu S, Kumar R, Bhushan D, Kumar S, Kumar A, Priyadarshi RN, Anand U. Open-label randomized controlled study of salt-restricted vs salt-unrestricted diet in cirrhosis patients with hyponatremia. World J Methodol 2026; 16(2): 112692 |
| URL |
https://www.wjgnet.com/2222-0682/full/v16/i2/112692.htm |
| DOI |
https://dx.doi.org/10.5662/wjm.v16.i2.112692 |
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