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Articles Published Processes
2/11/2026 3:41:43 AM | Browse: 1 | Download: 0
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Received |
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2025-08-05 00:59 |
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Peer-Review Started |
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2025-08-05 00:59 |
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First Decision by Editorial Office Director |
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2025-08-27 08:17 |
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Return for Revision |
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2025-08-27 08:17 |
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Revised |
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2025-09-11 06:33 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-26 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-26 09:12 |
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Articles in Press |
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2025-11-26 09:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-22 08:57 |
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Publish the Manuscript Online |
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2026-02-11 03:41 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Anesthesiology |
| Manuscript Type |
Minireviews |
| Article Title |
Gut-brain axis and post-operative cognitive dysfunction: A multifactorial perspective on microbiota, inflammation, and cognitive health
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rhythm Joshi, Nishkarsh Gupta, Anju Gupta, Puneet Khanna, Nishant Verma and Simran Kaur |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Anju Gupta, Assistant Professor, Associate Professor, MD, Department of Anesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India. dranjugupta09@gmail.com |
| Key Words |
Gut-brain axis; Post-operative cognitive dysfunction; Gut microbiota; Akkermansia muciniphila; Neuroinflammation; Short-chain fatty acids; Gut dysbiosis; Cognitive outcomes after surgery; Probiotic intervention; Microbiota-based targeted therapy |
| Core Tip |
This review explores the important connection between gut health and brain function, especially in patients recovering from surgery. It focuses on how disturbances in gut microbes after surgery can lead to inflammation, impaired gut barrier function, and memory issues—collectively known as post-operative cognitive dysfunction. The article highlights growing evidence that restoring gut balance using probiotics and other microbiota-based therapies may help reduce inflammation and support better cognitive recovery. By drawing attention to the gut-brain link, this review opens up new possibilities for non-invasive strategies to protect the brain and improve mental clarity in post-surgical patients. |
| Publish Date |
2026-02-11 03:41 |
| Citation |
Joshi R, Gupta N, Gupta A, Khanna P, Verma N, Kaur S. Gut-brain axis and post-operative cognitive dysfunction: A multifactorial perspective on microbiota, inflammation, and cognitive health. World J Gastrointest Pharmacol Ther 2026; 17(1): 112754 |
| URL |
https://www.wjgnet.com/2150-5349/full/v17/i1/112754.htm |
| DOI |
https://dx.doi.org/10.4292/wjgpt.v17.i1.112754 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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