| ISSN |
2308-3840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Anesthesiology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Safety and efficacy of dexmedetomidine for flexible bronchoscopy: A systematic review and meta-analysis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Amna Hassni, Abdul Hannan Siddiqui, Mahdeem Shahid, Abia Shariq, Huma Anwar, Khizra Nadeem, Alina Anjum, Hamida Memon, Ameer Talha, Sarosh Khan, Yusra Faisal, Maheen Naveed, Abdul Moeed and Salim Surani |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Abdul Hannan Siddiqui, Researcher, Department of Internal Medicine, Dow University of Health Sciences, Mission Road, Karachi 74200, Sindh, Pakistan. abdul.siddiqui19@dmc.duhs.edu.pk |
| Key Words |
Analgesia; Dexmedetomidine; Flexible bronchoscopy; Midazolam; Propofol; Sedation; Meta-analysis |
| Core Tip |
This meta-analysis assessed the effectiveness of dexmedetomidine (DEX), a selective alpha-2 adrenergic receptor agonist, as a sedative agent in flexible bronchoscopy. Compared with other sedative and analgesic regimens, DEX notably reduced the risk of hypoxemia and tachycardia, while mildly improving patient and physician satisfaction. Although extra sedation was administered where necessary, the overall safety profiles were favorable. These findings suggest that DEX is a promising option for patients with compromised respiratory capacity, providing enhanced safety and tolerability during bronchoscopy. |
| Publish Date |
2026-03-10 06:59 |
| Citation |
Hassni A, Siddiqui AH, Shahid M, Shariq A, Anwar H, Nadeem K, Anjum A, Memon H, Talha A, Khan S, Faisal Y, Naveed M, Moeed A, Surani S. Safety and efficacy of dexmedetomidine for flexible bronchoscopy: A systematic review and meta-analysis. World J Meta-Anal 2026; 14(1): 112793 |
| URL |
https://www.wjgnet.com/2308-3840/full/v14/i1/112793.htm |
| DOI |
https://dx.doi.org/10.13105/wjma.v14.i1.112793 |
