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12/15/2025 9:46:05 AM | Browse: 8 | Download: 5
Publication Name World Journal of Diabetes
Manuscript ID 112799
Country Spain
Received
2025-08-22 09:14
Peer-Review Started
2025-08-22 09:15
First Decision by Editorial Office Director
2025-09-04 10:44
Return for Revision
2025-09-06 14:10
Revised
2025-09-16 15:03
Publication Fee Transferred
2025-09-24 18:06
Second Decision by Editor
2025-10-30 05:38
Second Decision by Editor-in-Chief
2025-11-02 18:26
Final Decision by Editorial Office Director
2025-11-05 07:18
Articles in Press
2025-11-05 07:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-04 01:49
Publish the Manuscript Online
2025-12-15 09:46
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Longitudinal assessment of pancreatic exocrine dysfunction in type 1 diabetes
Manuscript Source Unsolicited Manuscript
All Author List Federico Bolado, Lucía Zabalza, Joaquín de-Carlos, Ibai Tamayo-Rodríguez, Carlos Prieto-Martínez and Nerea Hervás-Palacios
ORCID
Author(s) ORCID Number
Federico Bolado http://orcid.org/0000-0003-1522-2434
Lucía Zabalza http://orcid.org/0000-0001-7235-6864
Joaquín de-Carlos http://orcid.org/0000-0001-5875-4524
Ibai Tamayo-Rodríguez http://orcid.org/0000-0003-2860-3359
Funding Agency and Grant Number
Corresponding Author Federico Bolado, Associate Professor, MD, PhD, Department of Gastroenterology, Hospital Universitario de Navarra, Calle Irunlarrea 3, Pamplona 31003, Navarre, Spain. federico.bolado@unavarra.es
Key Words Exocrine pancreatic insufficiency; Fecal elastase-1; Pancreatic exocrine function; Diabetes-related complications; Type 1 diabetes
Core Tip This is the first study to investigate exocrine pancreatic dysfunction in individuals with type 1 diabetes (T1D) using fecal elastase in a longitudinal design. Our findings suggest that pancreatic exocrine function is frequently altered in T1D and may decline over time. However, the underlying pathophysiology remains unclear, and the clinical impact appears limited. Therefore, low fecal elastase levels in T1D should be interpreted with caution to avoid overdiagnosis and unnecessary treatment.
Publish Date 2025-12-15 09:46
Citation

Bolado F, Zabalza L, de-Carlos J, Tamayo-Rodríguez I, Prieto-Martínez C, Hervás-Palacios N. Longitudinal assessment of pancreatic exocrine dysfunction in type 1 diabetes. World J Diabetes 2025; 16(12): 112799

URL https://www.wjgnet.com/1948-9358/full/v16/i12/112799.htm
DOI https://dx.doi.org/10.4239/wjd.v16.i12.112799
Full Article (PDF) WJD-16-112799-with-cover.pdf
Manuscript File 112799_Auto_Edited_021232.docx
Answering Reviewers 112799-answering-reviewers.pdf
Audio Core Tip 112799-audio.m4a
Biostatistics Review Certificate 112799-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 112799-conflict-of-interest-statement.pdf
Copyright License Agreement 112799-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 112799-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 112799-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 112799-non-native-speakers.pdf
Supplementary Material 112799-supplementary-material.pdf
Peer-review Report 112799-peer-reviews.pdf
Journal Editor-in-Chief Review Report 112799-journal-editor-in-chief.pdf
Scientific Misconduct Check 112799-scientific-misconduct-check.png
Scientific Editor Work List 112799-scientific-editor-work-list.pdf
CrossCheck Report 112799-crosscheck-report.pdf