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Articles Published Processes
1/27/2026 10:12:31 AM | Browse: 0 | Download: 0
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Received |
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2025-08-07 01:54 |
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Peer-Review Started |
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2025-08-07 01:54 |
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First Decision by Editorial Office Director |
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2025-08-27 08:22 |
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Return for Revision |
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2025-08-27 08:22 |
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Revised |
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2025-09-18 09:46 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-01 03:10 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-02 03:40 |
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Articles in Press |
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2025-12-02 03:40 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-13 06:35 |
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Publish the Manuscript Online |
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2026-01-27 10:12 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Review |
| Article Title |
Evaluation methods of hepatic steatosis: From conventional techniques to emerging biomarkers
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kengo Moriyama |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kengo Moriyama, MD, PhD, Professor, Department of Clinical Health Science, Tokai University School of Medicine, 1838 Ishikawa-machi, Hachioji 1920032, Tōkyō, Japan. kengomoriyama@tokai.ac.jp |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Hepatic steatosis; Magnetic resonance imaging-derived proton density fat fraction; Controlled attenuation parameter; Blood-based biomarkers; Artificial intelligence; DNA methylation |
| Core Tip |
This review provides a comprehensive overview of hepatic steatosis evaluation methods, ranging from conventional ultrasound and liver biopsy to advanced techniques such as magnetic resonance imaging-derived proton density fat fraction, attenuation-based ultrasound, and emerging blood-based and epigenetic biomarkers. By integrating multimodal diagnostic strategies, including artificial intelligence-assisted imaging and methylation profiling, clinicians can improve the diagnosis, risk stratification, and therapeutic monitoring of metabolic dysfunction-associated steatotic liver disease. The review also highlights the evolving role of steatosis quantification as a treatment response marker and future directions in precision hepatology. |
| Publish Date |
2026-01-27 10:12 |
| Citation |
Moriyama K. Evaluation methods of hepatic steatosis: From conventional techniques to emerging biomarkers. World J Hepatol 2026; 18(1): 112821 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i1/112821.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i1.112821 |
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