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12/25/2025 8:27:22 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 112841
Country United States
Received
2025-08-08 05:36
Peer-Review Started
2025-08-08 05:37
First Decision by Editorial Office Director
2025-08-22 08:09
Return for Revision
2025-08-22 08:09
Revised
2025-09-03 08:20
Publication Fee Transferred
Second Decision by Editor
2025-10-30 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-30 06:16
Articles in Press
2025-10-30 06:16
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-15 00:50
Publish the Manuscript Online
2025-12-25 08:27
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Systematic Reviews
Article Title Impact of statin therapy on postoperative outcomes following colorectal cancer surgery: A systematic review
Manuscript Source Invited Manuscript
All Author List Sana Mohsin, Misha Hasan, Fatima Mustafa, Jai Kumar, Maryam Aleissa, Jasneet S Bhullar and Sarwan Kumar
ORCID
Author(s) ORCID Number
Sana Mohsin http://orcid.org/0009-0000-1445-2110
Jasneet S Bhullar http://orcid.org/0000-0003-2847-7751
Funding Agency and Grant Number
Corresponding Author Jasneet S Bhullar, Department of Surgery-Colon and Rectal Surgery, Ascension Providence Hospital, Michigan State University, 16001 West 9 Mile Road, Southfield, MI 48075, United States. drjsbhullar@gmail.com
Key Words Colorectal cancer; Statin; 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor; Postoperative complications; Anastomotic leak; Mortality; Surgical site infection
Core Tip This review evaluates the impact of statin therapy on postoperative outcomes following colorectal cancer surgery. The study focuses on cohort studies to show how statin use, particularly its timing and duration, may affect the risk of anastomotic leaks, surgical site infection, and short-term mortality. Despite conflicting data, a consistent trend toward reduced 30-day mortality was observed. Overall, these findings suggest the potential role of statins in colorectal cancer surgery, however due to the heterogeneity in definitions of statin therapy and limitations of study design there is a need for prospective studies to confirm their role in improving postsurgical outcomes.
Publish Date 2025-12-25 08:27
Citation

Mohsin S, Hasan M, Mustafa F, Kumar J, Aleissa M, Bhullar JS, Kumar S. Impact of statin therapy on postoperative outcomes following colorectal cancer surgery: A systematic review. World J Gastrointest Surg 2025; 17(12): 112841

URL https://www.wjgnet.com/1948-9366/full/v17/i12/112841.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i12.112841
Full Article (PDF) WJGS-17-112841-with-cover.pdf
PRISMA 2009 Checklist 112841-PRISMA-2009-Checklist.pdf
Manuscript File 112841_Auto_Edited_011236.docx
Answering Reviewers 112841-answering-reviewers.pdf
Audio Core Tip 112841-audio.mp3
Conflict-of-Interest Disclosure Form 112841-conflict-of-interest-statement.pdf
Copyright License Agreement 112841-copyright-assignment.pdf
Peer-review Report 112841-peer-reviews.pdf
Scientific Misconduct Check 112841-scientific-misconduct-check.png
Scientific Editor Work List 112841-scientific-editor-work-list.pdf
CrossCheck Report 112841-crosscheck-report.pdf