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11/14/2025 8:23:13 AM | Browse: 6 | Download: 44
Publication Name World Journal of Diabetes
Manuscript ID 112847
Country South Africa
Received
2025-08-07 02:04
Peer-Review Started
2025-08-07 06:25
To Make the First Decision
Return for Revision
2025-08-22 09:06
Revised
2025-08-31 20:19
Second Decision
2025-09-22 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-22 05:56
Articles in Press
2025-09-22 05:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-06 07:55
Publish the Manuscript Online
2025-11-14 08:23
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Review
Article Title Mechanisms behind the anti-diabetic and anti-obesity effects of seaweeds or macroalgae and their bioactive compounds
Manuscript Source Invited Manuscript
All Author List S'thandiwe Nozibusiso Magwaza and Md Shahidul Islam
ORCID
Author(s) ORCID Number
Md Shahidul Islam http://orcid.org/0000-0003-0309-9491
Funding Agency and Grant Number
Funding Agency Grant Number
India-South Africa Bilateral Research Grant from the National Research Foundation, Pretoria, South Africa 133137
Corresponding Author Md Shahidul Islam, Full Professor, Head, PhD, Professor, Senior Scientist, Department of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, University Road, Chiltern Hills, Durban 4000, KwaZulu-Natal, South Africa. islamd@ukzn.ac.za
Key Words Diabetes; Gut microbiota; Inflammation; Insulin sensitivity; Lipogenesis; Macroalgae; Obesity; Oxidative stress; Seaweeds; Bioactive compounds
Core Tip Obesity and diabetes are global health challenges with increasing prevalence and strong associations with cardiovascular disease, stroke, and certain cancers. While pharmacological treatments exist, the demand for natural, bioactive-based interventions remains critical. Seaweeds have garnered significant attention due to their diverse bioactive compounds with demonstrated anti-obesity and anti-diabetic properties. This review elucidates the mechanisms by which seaweed regulates metabolic disorders. Key actions include modulation of adipogenesis, appetite suppression, regulation of gut microbiota, enhancement of insulin sensitivity, and attenuation of inflammation and oxidative stress. Together, these mechanisms provide insights into how seaweeds specifically target obesity and diabetes.
Publish Date 2025-11-14 08:23
Citation <p>Magwaza SN, Islam MS. Mechanisms behind the anti-diabetic and anti-obesity effects of seaweeds or macroalgae and their bioactive compounds. <i>World J Diabetes</i> 2025; 16(11): 112847</p>
URL https://www.wjgnet.com/1948-9358/full/v16/i11/112847.htm
DOI https://dx.doi.org/10.4239/wjd.v16.i11.112847
Full Article (PDF) WJD-16-112847-with-cover.pdf
Manuscript File 112847_Auto_Edited_095335.docx
Answering Reviewers 112847-answering-reviewers.pdf
Audio Core Tip 112847-audio.mp3
Conflict-of-Interest Disclosure Form 112847-conflict-of-interest-statement.pdf
Copyright License Agreement 112847-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 112847-non-native-speakers.pdf
Peer-review Report 112847-peer-reviews.pdf
Scientific Misconduct Check 112847-scientific-misconduct-check.png
Scientific Editor Work List 112847-scientific-editor-work-list.pdf
CrossCheck Report 112847-crosscheck-report.pdf