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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 112853
Country China
Received
2025-08-08 05:59
Peer-Review Started
2025-08-08 05:59
First Decision by Editorial Office Director
2025-08-22 08:34
Return for Revision
2025-08-22 08:34
Revised
2025-09-05 02:27
Publication Fee Transferred
2025-09-08 06:31
Second Decision by Editor
2025-10-20 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-20 07:10
Articles in Press
2025-10-20 07:10
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-26 09:36
Publish the Manuscript Online
2025-12-11 08:20
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Long-term survival after treatment of gastric cancer with S-1 plus oxaliplatin regimen and sintilimab: A case report
Manuscript Source Unsolicited Manuscript
All Author List Jun Pan, Ping Li, Yu-He Zhou, Ting-Ting Pan, Yi-Tian Chen and Xiao-Yuan Chu
ORCID
Author(s) ORCID Number
Xiao-Yuan Chu http://orcid.org/0009-0009-3440-6467
Funding Agency and Grant Number
Corresponding Author Xiao-Yuan Chu, MD, Department of Oncology, Jinling Hospital, Medical School of Nanjing University, No. 305 Zhongshan East Road, Nanjing 210002, Jiangsu Province, China. chuxiaoyuan0@163.com
Key Words Metastatic gastric cancer; Sintilimab; Immunotherapy; Chemotherapy; Progression-free survival; Case report
Core Tip Chemotherapy combined with immunotherapy is the standard first-line treatment for metastatic gastric cancer. However, the first-line median progression-free survival is only about 7 months. This article reports a case of metastatic gastric cancer in which the patient received S-1 plus oxaliplatin regimen with sintilimab, followed by maintenance therapy with S-1 and sintilimab. The patient achieved a partial response and a progression-free survival of 23 months. Moreover, the treatment was temporarily paused for 6 months due to pneumonia. However, upon re-evaluation 6 months later, the tumor continued to regress. This combination therapy has shown encouraging results and warrants further study.
Publish Date 2025-12-11 08:20
Citation

Pan J, Li P, Zhou YH, Pan TT, Chen YT, Chu XY. Long-term survival after treatment of gastric cancer with S-1 plus oxaliplatin regimen and sintilimab: A case report. World J Gastrointest Oncol 2025; 17(12): 112853

URL https://www.wjgnet.com/1948-5204/full/v17/i12/112853.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i12.112853
Full Article (PDF) WJGO-17-112853-with-cover.pdf