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12/11/2025 8:20:54 AM | Browse: 4 | Download: 12
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 112894
Country China
Received
2025-08-08 09:31
Peer-Review Started
2025-08-08 09:33
First Decision by Editorial Office Director
2025-09-01 08:21
Return for Revision
2025-09-01 08:21
Revised
2025-09-12 04:05
Publication Fee Transferred
Second Decision by Editor
2025-10-23 02:31
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-23 08:17
Articles in Press
2025-10-23 08:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-28 14:32
Publish the Manuscript Online
2025-12-11 08:20
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Novel insights into SLC16A8 in colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Jing-Yuan Li, Guang Ji and Yan-Qi Dang
ORCID
Author(s) ORCID Number
Guang Ji http://orcid.org/0000-0003-0842-3676
Yan-Qi Dang http://orcid.org/0000-0002-0316-7880
Funding Agency and Grant Number
Corresponding Author Yan-Qi Dang, Institute of Digestive Diseases, Longhua Hospital, China-Canada Center of Research for Digestive Diseases, Shanghai University of Traditional Chinese Medicine, Fenglin Road Sub-district, Shanghai 200032, China. dangyanqi9022@126.com
Key Words Solute carrier family 16 member 8; Colorectal cancer; Hypoxic; Glycolysis; Tumor microenvironment; Endothelium-mesenchymal transition; siRNA; Genes; Biomarker; Cancer
Core Tip Solute carrier family 16 member 8 (SLC16A8) drives the progression of the hypoxic microenvironment in colorectal cancer through dual mechanisms: Glycolytic reprogramming mediated by HIF-1α and endothelium-mesenchymal transition. Targeting SLC16A8 synergistically inhibits metabolic adaptation and vascular remodeling, demonstrating potential for clinical translation.
Publish Date 2025-12-11 08:20
Citation

Li JY, Ji G, Dang YQ. Novel insights into SLC16A8 in colorectal cancer. World J Gastrointest Oncol 2025; 17(12): 112894

URL https://www.wjgnet.com/1948-5204/full/v17/i12/112894.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i12.112894
Full Article (PDF) WJGO-17-112894-with-cover.pdf
Manuscript File 112894_Auto_Edited_022851.docx
Answering Reviewers 112894-answering-reviewers.pdf
Audio Core Tip 112894-audio.m4a
Conflict-of-Interest Disclosure Form 112894-conflict-of-interest-statement.pdf
Copyright License Agreement 112894-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 112894-non-native-speakers.pdf
Peer-review Report 112894-peer-reviews.pdf
Scientific Misconduct Check 112894-scientific-misconduct-check.png
Scientific Editor Work List 112894-scientific-editor-work-list.pdf
CrossCheck Report 112894-crosscheck-report.pdf