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Articles Published Processes
12/22/2025 7:43:02 AM | Browse: 1 | Download: 1
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Received |
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2025-08-11 01:36 |
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Peer-Review Started |
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2025-08-11 01:36 |
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First Decision by Editorial Office Director |
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2025-09-01 08:54 |
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Return for Revision |
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2025-09-01 08:54 |
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Revised |
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2025-09-13 19:38 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-20 05:06 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-20 05:07 |
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Articles in Press |
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2025-11-20 05:07 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-15 00:57 |
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Publish the Manuscript Online |
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2025-12-22 07:43 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Gut microbiota as a potential predictor of therapeutic response in adults with Crohn’s disease: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Amit Kumar Dutta, Subitha Vishruth, Sai Lakshmi Kovi, Piyush Dadhich, Jagadish Polavarapu and Dilip Abraham |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Amit Kumar Dutta, FRCPE, Professor, Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Ground Floor, Williams Building, Vellore 632004, Tamil Nadu, India. akdutta1995@yahoo.co.in |
| Key Words |
Gut microbiota; Crohn’s disease; Therapy; Predictor; Diversity; Bacteria |
| Core Tip |
Crohn’s disease is a chronic inflammatory bowel condition requiring lifelong therapy. However, about one-third of patients do not respond to any particular treatment, and a change of therapy is needed. There is a need for identifying predictors of therapy before treatment to avoid non-response, but such markers are uncommon. Accumulating evidence suggests that the gut bacterial population can serve as a potentially useful prediction tool. In this review, we have presented the current status of the role of gut microbial community as a biomarker of response. The results are encouraging but further work is needed before they can be used in clinical practice. |
| Publish Date |
2025-12-22 07:43 |
| Citation |
Dutta AK, Vishruth S, Kovi SL, Dadhich P, Polavarapu J, Abraham D. Gut microbiota as a potential predictor of therapeutic response in adults with Crohn’s disease: A systematic review. World J Gastrointest Pathophysiol 2025; 16(4): 112961 |
| URL |
https://www.wjgnet.com/2150-5330/full/v16/i4/112961.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v16.i4.112961 |
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