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Articles Published Processes
12/27/2025 2:50:52 AM | Browse: 0 | Download: 0
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Received |
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2025-08-12 06:05 |
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Peer-Review Started |
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2025-08-12 06:06 |
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First Decision by Editorial Office Director |
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2025-09-03 10:09 |
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Return for Revision |
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2025-09-03 10:09 |
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Revised |
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2025-09-16 06:17 |
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Publication Fee Transferred |
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2025-09-22 00:14 |
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Second Decision by Editor |
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2025-11-12 02:49 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-12 10:41 |
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Articles in Press |
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2025-11-12 10:41 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-15 09:05 |
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Publish the Manuscript Online |
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2025-12-27 02:50 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Retrospective Study |
| Article Title |
Serum uric acid-to-high-density lipoprotein cholesterol ratio and cardiovascular risk in Asian patients with metabolic dysfunction-associated steatotic liver disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yang Wang, Guang-Hui Ma, Ming-Yue Qu, Qi-Shui Xu and Hai-Xia Huang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shanghai Health and Medical Center Star Talent Program |
2023QMX11 |
| Shanghai Health and Medical Center Star Talent Program |
2023QMX01 |
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| Corresponding Author |
Qi-Shui Xu, Department of Anesthesiology, Wuxi No. 2 Chinese Medicine Hospital, No. 390 Xincheng Road, Taihu Sub-district, Binhu District, Wuxi 214121, Jiangsu Province, China. 810204666@qq.com |
| Key Words |
Cardiovascular risk; Framingham risk score; Metabolic dysfunction-associated steatotic liver disease; Receiver operating characteristic curve; Serum uric acid-to-high-density lipoprotein cholesterol ratio |
| Core Tip |
This study demonstrated that an elevated uric acid-to-high-density lipoprotein cholesterol ratio (UHR) was independently associated with a higher predicted 10-year CVD risk, as estimated by the Framingham risk score, in a large cohort of Asian patients with metabolic dysfunction-associated steatotic liver disease. A distinct linear dose-response association between increasing UHR levels and CVD risk was observed. Notably, UHR exhibited superior predictive performance compared with conventional biomarkers (area under the curve = 0.655), with an optimal cutoff value of 292. Readily obtainable from routine biochemical testing, UHR thus represents a simple and cost-effective indicator for early CVD risk stratification in patients with metabolic dysfunction-associated steatotic liver disease. |
| Publish Date |
2025-12-27 02:50 |
| Citation |
Wang Y, Ma GH, Qu MY, Xu QS, Huang HX. Serum uric acid-to-high-density lipoprotein cholesterol ratio and cardiovascular risk in Asian patients with metabolic dysfunction-associated steatotic liver disease. World J Gastroenterol 2025; 31(48): 112972 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i48/112972.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i48.112972 |
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