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Articles Published Processes
11/14/2025 12:56:15 AM | Browse: 0 | Download: 0
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Received |
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2025-08-12 06:26 |
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Peer-Review Started |
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2025-08-12 06:29 |
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To Make the First Decision |
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Return for Revision |
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2025-08-22 08:35 |
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Revised |
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2025-08-30 16:55 |
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Second Decision |
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2025-10-11 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-10-11 05:40 |
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Articles in Press |
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2025-10-11 05:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-20 10:14 |
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Publish the Manuscript Online |
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2025-11-14 00:56 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Survival prognosis in advanced HER-2 negative gastric cancer treated with immunochemotherapy: A novel model
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zhi-Yuan Yao, Gang Bao, Geng-Chen Li, Qiu-Lin Hao, Li-Jie Ma, Yue-Xuan Rao, Ke Xu, Xiao Ma and Zheng-Xiang Han |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Zheng-Xiang Han, PhD, Professor, Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, No. 99 Huaihai West Road, Xuzhou 221000, Jiangsu Province, China. xzpxlgc@163.com |
| Key Words |
Gastric cancer; Programmed death-1 inhibitor; Predictive model; Neutrophil-to-lymphocyte ratio; C-reactive protein-albumin-lymphocyte index; Efficacy |
| Core Tip |
This study developed and validated a novel survival prediction model for advanced HER-2 negative gastric cancer patients receiving immunotherapy combined with chemotherapy. A retrospective analysis of 200 patients identified programmed death ligand 1 expression, microsatellite instability, tumor-node-metastasis stage, tumor differentiation, neutrophil-to-lymphocyte ratio, and C-reactive protein-albumin-lymphocyte index as independent prognostic factors. Based on these factors, nomogram models for progression-free survival and overall survival were constructed and validated using the concordance index (C-index) and area under the curve. The results showed good discrimination ability in both the training and validation sets, indicating that the model effectively predicts patient survival outcomes and provides strong support for personalized treatment decisions. |
| Publish Date |
2025-11-14 00:56 |
| Citation |
<p>Yao ZY, Bao G, Li GC, Hao QL, Ma LJ, Rao YX, Xu K, Ma X, Han ZX. Survival prognosis in advanced HER-2 negative gastric cancer treated with immunochemotherapy: A novel model. <i>World J Gastrointest Oncol</i> 2025; 17(11): 112981</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i11/112981.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i11.112981 |
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