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12/25/2025 3:52:07 AM | Browse: 11 | Download: 36
Publication Name World Journal of Stem Cells
Manuscript ID 112990
Country Türkiye
Received
2025-08-12 07:48
Peer-Review Started
2025-08-12 07:54
First Decision by Editorial Office Director
2025-09-16 09:03
Return for Revision
2025-09-16 09:03
Revised
2025-09-27 22:01
Publication Fee Transferred
Second Decision by Editor
2025-10-30 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-06 09:44
Articles in Press
2025-11-06 09:44
Edit the Manuscript by Language Editor
2025-11-10 20:33
Typeset the Manuscript
2025-12-18 03:05
Publish the Manuscript Online
2025-12-25 03:52
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Breast cancer stem cells and circulating tumor cells: Dual drivers of progression and relapse
Manuscript Source Invited Manuscript
All Author List Zahra Azizi, Buket Er Urganci and Ibrahim Acikbas
ORCID
Author(s) ORCID Number
Zahra Azizi http://orcid.org/0009-0007-7234-432X
Funding Agency and Grant Number
Corresponding Author Zahra Azizi, Department of Medical Biology, Faculty of Medicine, Pamukkale University, Kinikli Road, Denizli 20160, Türkiye. zazizi19@posta.pau.edu.tr
Key Words Breast neoplasms; Neoplastic stem cells; Circulating tumor cells; Metastasis; Treatment-resistant
Core Tip This review emphasizes the dual functions of breast cancer stem cells and circulating tumor cells (CTCs) in the advancement of tumors, resistance to treatment, and metastasis. We examine their common molecular characteristics, including self-renewal and epithelial-mesenchymal transition, as well as their interaction with the tumor microenvironment. The paper also covers the current technologies for detecting CTCs and their clinical applications. Gaining an understanding of the dynamic relationship between breast cancer stem cells and CTCs provides valuable insights into the early detection of metastasis and may inform the development of personalized treatment strategies for breast cancer patients.
Publish Date 2025-12-25 03:52
Citation

Azizi Z, Er Urganci B, Acikbas I. Breast cancer stem cells and circulating tumor cells: Dual drivers of progression and relapse. World J Stem Cells 2025; 17(12): 112990

URL https://www.wjgnet.com/1948-0210/full/v17/i12/112990.htm
DOI https://dx.doi.org/10.4252/wjsc.v17.i12.112990
Full Article (PDF) WJSC-17-112990-with-cover.pdf
Manuscript File 112990_Auto_Edited_021845.docx
Answering Reviewers 112990-answering-reviewers.pdf
Audio Core Tip 112990-audio.mp3
Conflict-of-Interest Disclosure Form 112990-conflict-of-interest-statement.pdf
Copyright License Agreement 112990-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 112990-non-native-speakers.pdf
Peer-review Report 112990-peer-reviews.pdf
Scientific Misconduct Check 112990-scientific-misconduct-check.png
Scientific Editor Work List 112990-scientific-editor-work-list.pdf
CrossCheck Report 112990-crosscheck-report.pdf