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11/14/2025 8:23:18 AM | Browse: 8 | Download: 66
Publication Name World Journal of Diabetes
Manuscript ID 112999
Country Israel
Received
2025-08-12 02:23
Peer-Review Started
2025-08-13 00:11
To Make the First Decision
Return for Revision
2025-09-03 03:12
Revised
2025-09-14 08:24
Second Decision
2025-10-13 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-10-20 10:31
Articles in Press
2025-10-20 10:31
Publication Fee Transferred
2025-09-15 04:50
Edit the Manuscript by Language Editor
2025-10-22 04:48
Typeset the Manuscript
2025-11-06 08:08
Publish the Manuscript Online
2025-11-14 08:23
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Retrospective Study
Article Title Glucagon-like peptide 1 receptor agonists switching patterns in type two diabetes: A retrospective real-world study
Manuscript Source Unsolicited Manuscript
All Author List Sameer Kassem, Buthaina Khalaila, Nili Stein and Adnan Zaina
ORCID
Author(s) ORCID Number
Sameer Kassem http://orcid.org/0000-0003-3588-0338
Funding Agency and Grant Number
Corresponding Author Sameer Kassem, Head, Department of Internal Medicine, Technion Israel Institute of Technology, Michal 7, Haifa 3436212, Israel. sameerk@technion.ac.il
Key Words Type 2 diabetes mellitus; Glucagon-like peptide-1 receptor agonists; Glycated hemoglobin; Glycemic control; Switching; Real world
Core Tip This retrospective study analyzed the effects of switching between glucagon-like peptide-1 receptor agonists (GLP-1RA) in patients with type 2 diabetes mellitus. It found that 25.5% of over 70000 patients changed GLP-1RA regimens, with most experiencing significant glycated hemoglobin reductions, from 8.5% to 7.6%. Notably, switching from daily to weekly GLP-1RA was associated with the highest improvement rate (81%), demonstrating that such transitions are a practical and effective alternative to treatment intensification for better glycemic control.
Publish Date 2025-11-14 08:23
Citation <p>Kassem S, Khalaila B, Stein N, Zaina A. Glucagon-like peptide 1 receptor agonists switching patterns in type two diabetes: A retrospective real-world study. <i>World J Diabetes</i> 2025; 16(11): 112999</p>
URL https://www.wjgnet.com/1948-9358/full/v16/i11/112999.htm
DOI https://dx.doi.org/10.4239/wjd.v16.i11.112999
Full Article (PDF) WJD-16-112999-with-cover.pdf
Manuscript File 112999_Auto_Edited_032812.docx
Answering Reviewers 112999-answering-reviewers.pdf
Audio Core Tip 112999-audio.m4a
Biostatistics Review Certificate 112999-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 112999-conflict-of-interest-statement.pdf
Copyright License Agreement 112999-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 112999-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 112999-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 112999-non-native-speakers.pdf
Peer-review Report 112999-peer-reviews.pdf
Journal Editor-in-Chief Review Report 112999-journal-editor-in-chief.pdf
Scientific Misconduct Check 112999-scientific-misconduct-check.png
Scientific Editor Work List 112999-scientific-editor-work-list.pdf
CrossCheck Report 112999-crosscheck-report.pdf