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Articles Published Processes
1/30/2026 6:45:47 AM | Browse: 3 | Download: 1
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Received |
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2025-09-12 08:19 |
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Peer-Review Started |
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2025-09-12 08:19 |
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First Decision by Editorial Office Director |
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2025-10-13 03:09 |
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Return for Revision |
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2025-10-13 03:09 |
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Revised |
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2025-10-27 09:54 |
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Publication Fee Transferred |
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2025-11-03 02:49 |
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Second Decision by Editor |
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2025-11-18 01:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-18 06:43 |
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Articles in Press |
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2025-11-18 06:43 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-15 07:52 |
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Publish the Manuscript Online |
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2026-01-30 06:45 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Acupuncture on 5-hydroxytryptamine levels and clinical outcomes in depression: A systematic review and meta-analysis of randomized controlled trials
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi Wang, Peng-Tao Wu, Ittipalanukul Penpat, Fei-Cui Zeng, Qun Lu and Zhi-Hai Hu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Outstanding Young Medical Talents Training Program of the Health System in Pudong New District, Shanghai |
PWRq2023-37 |
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| Corresponding Author |
Zhi-Hai Hu, Associate Professor, Department of Acupuncture and Moxibusion, Shanghai TCM-Integrated Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No. 230, Baoding Road, Hongkou District, Shanghai 200082, China. shennong923@163.com |
| Key Words |
Acupuncture; Depression; Meta-analysis; 5-hydroxytryptamine; Sleep disturbance; Anxiety |
| Core Tip |
This meta-analysis focused exclusively on traditional manual acupuncture, excluding electroacupuncture, to determine its independent therapeutic effect on depression. Twenty randomized controlled trials were included. The findings reveal that acupuncture significantly improves depressive symptoms, anxiety, sleep quality, and serum 5-hydroxytryptamine levels, while reducing antidepressant-related side effects. By eliminating heterogeneity caused by different acupuncture modalities, this study provides stronger evidence for the clinical application of acupuncture as an effective adjunctive therapy for depression. |
| Publish Date |
2026-01-30 06:45 |
| Citation |
Wang Y, Wu PT, Penpat I, Zeng FC, Lu Q, Hu ZH. Acupuncture on 5-hydroxytryptamine levels and clinical outcomes in depression: A systematic review and meta-analysis of randomized controlled trials. World J Psychiatry 2026; 16(2): 113049 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i2/113049.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i2.113049 |
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