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3/13/2026 3:56:50 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 113096
Country Japan
Received
2025-08-27 11:26
Peer-Review Started
2025-08-27 11:27
First Decision by Editorial Office Director
2025-09-03 06:45
Return for Revision
2025-09-03 06:45
Revised
2025-11-20 09:30
Publication Fee Transferred
2025-11-21 01:48
Second Decision by Editor
2026-02-02 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-03 02:28
Articles in Press
2026-02-03 02:28
Edit the Manuscript by Language Editor
2026-02-10 22:21
Typeset the Manuscript
2026-03-03 03:00
Publish the Manuscript Online
2026-03-13 03:56
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Hereditary angioedema with recurrent abdominal pain in a patient with a novel SERPING1 gene mutation: A case report
Manuscript Source Unsolicited Manuscript
All Author List Ko Matsuura, Chie Ueda, Chinami Hashimura, Hiromasa Yakushiji and Takahiko Horiuchi
ORCID
Author(s) ORCID Number
Ko Matsuura http://orcid.org/0000-0001-5376-2576
Funding Agency and Grant Number
Corresponding Author Ko Matsuura, MD, Department of Gastroenterology, Kishiwada Tokushukai Hospital, 4-27-1 Kamori-cho, Kishiwada 596-0042, Osaka, Japan. matuurac90@gmail.com
Key Words C1 inhibitor; Complement C4; SERPING1 gene; Frameshift mutation; Hereditary angioedema; Gastrointestinal edema; Case report
Core Tip This study highlights that hereditary angioedema should be considered in cases of recurrent abdominal pain, even in the absence of typical edema or family history. Although the initial presentation mimicked acquired angioedema, the early onset prompted SERPING1 gene testing, revealing a novel frameshift mutation. This case emphasizes the importance of genetic confirmation for hereditary angioedema diagnosis in atypical cases, as timely diagnosis is crucial owing to the potentially life-threatening nature of the condition.
Publish Date 2026-03-13 03:56
Citation

Matsuura K, Ueda C, Hashimura C, Yakushiji H, Horiuchi T. Hereditary angioedema with recurrent abdominal pain in a patient with a novel SERPING1 gene mutation: A case report. World J Gastrointest Endosc 2026; 18(3): 113096

URL https://www.wjgnet.com/1948-5190/full/v18/i3/113096.htm
DOI https://dx.doi.org/10.4253/wjge.v18.i3.113096
Full Article (PDF) WJGE-18-113096-with-cover.pdf
CARE Checklist–2016 113096-CARE-Checklist-2016.pdf
Manuscript File 113096_Auto_Edited_091357.docx
Answering Reviewers 113096-answering-reviewers.pdf
Audio Core Tip 113096-audio.mp3
Conflict-of-Interest Disclosure Form 113096-conflict-of-interest-statement.pdf
Copyright License Agreement 113096-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 113096-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 113096-non-native-speakers.pdf
Peer-review Report 113096-peer-reviews.pdf
Scientific Misconduct Check 113096-scientific-misconduct-check.png
Scientific Editor Work List 113096-scientific-editor-work-list.pdf
CrossCheck Report 113096-crosscheck-report.pdf