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2/28/2026 8:32:55 AM | Browse: 2 | Download: 0
Publication Name World Journal of Psychiatry
Manuscript ID 113125
Country China
Received
2025-09-12 08:28
Peer-Review Started
2025-09-12 08:28
First Decision by Editorial Office Director
2025-10-13 03:11
Return for Revision
2025-10-13 03:11
Revised
2025-10-21 14:25
Publication Fee Transferred
Second Decision by Editor
2025-12-29 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-29 07:29
Articles in Press
2025-12-29 07:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-12 08:04
Publish the Manuscript Online
2026-02-28 08:32
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Review
Article Title Contemporary adolescent depression: Multidimensional analysis from neurobiological, psychological, and social integrative perspectives
Manuscript Source Unsolicited Manuscript
All Author List Yan-Li Ma, Xue Fu, Yu Chen and Shui-Xiu Zeng
ORCID
Author(s) ORCID Number
Shui-Xiu Zeng http://orcid.org/0009-0007-3318-4941
Funding Agency and Grant Number
Funding Agency Grant Number
Rising Stars of Medical Talents “Youth Development Program” No. 2023-62
Shanghai Fourth People’s Hospital Research Initiation Special Project No. sykyqd06601
Research on Health Policy of Shanghai Municipal Health Commission No. 2024HP01
Hongkou District Health Commission Medical Research Project No. Hongwei 2401-02
Hongkou District TCM Specialized Diseases/Clinics Construction Project No. HKGYQYXM-2026-12
Corresponding Author Shui-Xiu Zeng, Researcher, Department of Pediatrics, Shenzhen People's Hospital, No. 1017 Dongmen North Road, Luohu District, Shenzhen 518020, Guangdong Province, China. zengshuixiu121@163.com
Key Words Adolescent depression; Multidimensional analysis; Neurobiology; Psychological factors; Social environment; Integrative intervention
Core Tip This review applies a bio-psycho-social model to comprehensively examine adolescent depression, integrating neurobiological, psychological, and social perspectives. It synthesizes recent evidence on neural circuit dysfunction, hypothalamic-pituitary-adrenal axis dysregulation, cognitive biases, maladaptive emotion regulation, perfectionism, attachment patterns, and environmental risk factors such as social media use and family dysfunction. The article emphasizes the interplay among these domains and highlights the need for personalized, multidimensional prevention and intervention strategies to improve outcomes for adolescents with depression.
Publish Date 2026-02-28 08:32
Citation

Ma YL, Fu X, Chen Y, Zeng SX. Contemporary adolescent depression: Multidimensional analysis from neurobiological, psychological, and social integrative perspectives. World J Psychiatry 2026; 16(3): 113125

URL https://www.wjgnet.com/2220-3206/full/v16/i3/113125.htm
DOI https://dx.doi.org/10.5498/wjp.v16.i3.113125
Full Article (PDF) WJP-16-113125-with-cover.pdf
Manuscript File 113125_Auto_Edited_091226.docx
Answering Reviewers 113125-answering-reviewers.pdf
Audio Core Tip 113125-audio.mp3
Conflict-of-Interest Disclosure Form 113125-conflict-of-interest-statement.pdf
Copyright License Agreement 113125-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 113125-non-native-speakers.pdf
Peer-review Report 113125-peer-reviews.pdf
Scientific Misconduct Check 113125-scientific-misconduct-check.png
Scientific Editor Work List 113125-scientific-editor-work-list.pdf
CrossCheck Report 113125-crosscheck-report.pdf