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Articles Published Processes
1/15/2026 3:35:07 AM | Browse: 2 | Download: 12
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Received |
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2025-08-18 07:24 |
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Peer-Review Started |
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2025-08-18 07:24 |
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First Decision by Editorial Office Director |
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2025-09-09 09:58 |
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Return for Revision |
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2025-09-09 09:58 |
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Revised |
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2025-09-17 09:06 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-03 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-03 06:30 |
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Articles in Press |
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2025-12-03 06:30 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-05 01:28 |
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Publish the Manuscript Online |
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2026-01-15 03:35 |
| ISSN |
1948-5190 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Science of fecal microbiota transplant: From history to cutting-edge clinical practice
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Praveen Kumar Uppala, Sita K Karanam and Ramaiah Maddi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Praveen Kumar Uppala, Assistant Professor, Researcher, Department of Pharmacology, Maharajah’s College of Pharmacy, Phool Baugh, Vizianagaram 535002, Andhra Pradesh, India. praveen.chintu32@gmail.com |
| Key Words |
Fecal microbiota transplantation; Clostridioides difficile infections; Inflammatory bowel disease; Irritable bowel syndrome; Gut microbiome; Conventional antibiotics |
| Core Tip |
Fecal microbiota transplantation (FMT) has evolved from an ancient remedy into a scientifically validated, high-efficacy treatment for recurrent Clostridioides difficile infection, with growing potential for managing other diseases linked to gut dysbiosis. This article explores FMT’s historical origins, mechanisms of action, clinical applications, safety concerns, and regulatory challenges. It emphasizes the need for standardized protocols, rigorous donor screening, and long-term monitoring to ensure safe and effective clinical integration. As microbiome science advances, FMT stands at the frontier of personalized, microbiota-based therapeutics. |
| Publish Date |
2026-01-15 03:35 |
| Citation |
Uppala PK, Karanam SK, Maddi R. Science of fecal microbiota transplant: From history to cutting-edge clinical practice. World J Gastrointest Endosc 2026; 18(1): 113133 |
| URL |
https://www.wjgnet.com/1948-5190/full/v18/i1/113133.htm |
| DOI |
https://dx.doi.org/10.4253/wjge.v18.i1.113133 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
