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Articles Published Processes
11/20/2025 7:56:48 AM | Browse: 20 | Download: 28
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Received |
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2025-08-18 01:11 |
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Peer-Review Started |
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2025-08-18 01:11 |
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First Decision by Editorial Office Director |
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2025-09-30 09:38 |
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Return for Revision |
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2025-09-30 09:38 |
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Revised |
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2025-09-30 12:34 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-22 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-22 03:58 |
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Articles in Press |
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2025-10-22 03:58 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-07 00:33 |
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Publish the Manuscript Online |
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2025-11-20 07:56 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Letter to the Editor |
| Article Title |
From rescue to recovery: Reframing severe alcoholic hepatitis management through 90-day survival
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Amira A A Othman |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Amira A A Othman, Chief Physician, MD, PhD, Professor, Department of Internal Medicine, Suez University, Cairo-Suez Road, Suez 43511, Egypt. amira.othman@med.suezuni.edu.eg |
| Key Words |
Severe alcoholic hepatitis; Alcohol-associated hepatitis; Corticosteroids; 90-day survival; Fecal microbiota transplantation; Granulocyte colony-stimulating factor; Liver transplantation; Steroid non-response; Composite endpoints |
| Core Tip |
Severe alcoholic hepatitis (SAH) is characterized by high short-term mortality, yet traditional 28-day endpoints overlook late complications that often determine recovery. This manuscript highlights a systematic review advocating 90-day survival as a more meaningful metric, capturing threats such as infections, renal decline, and relapse. Emerging therapies, fecal microbiota transplantation and granulocyte colony-stimulating factor, show potential in this extended window, particularly for corticosteroid non-responders. A proposed two-phase care model, early stabilization followed by recovery consolidation, may bridge the gap between initial rescue and sustained remission in SAH. |
| Publish Date |
2025-11-20 07:56 |
| Citation |
Othman AAA. From rescue to recovery: Reframing severe alcoholic hepatitis management through 90-day survival. World J Gastroenterol 2025; 31(43): 113141 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i43/113141.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i43.113141 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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