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6/4/2026 7:37:43 AM | Browse: 0 | Download: 0
Publication Name World Journal of Biological Chemistry
Manuscript ID 113144
Country India
Received
2025-08-18 01:51
Peer-Review Started
2025-08-18 01:51
First Decision by Editorial Office Director
2025-09-12 06:28
Return for Revision
2025-09-12 06:28
Revised
2025-09-24 07:32
Publication Fee Transferred
Second Decision by Editor
2026-01-28 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-28 07:37
Articles in Press
2026-01-28 07:37
Edit the Manuscript by Language Editor
2026-03-06 20:22
Typeset the Manuscript
2026-05-27 07:47
Publish the Manuscript Online
2026-06-04 07:37
ISSN 1949-8454 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Chemistry, Medicinal
Manuscript Type Basic Study
Article Title Study of Tinospora cordifolia stem and Senna siamea leaf and pods: An in vitro therapeutic approach for leukemia
Manuscript Source Invited Manuscript
All Author List Arthi Boro, Abidharini Jothi Dheivasikamani, Antony Prabhu Jeyabal Philomenathan, Jeganathan Manivannan, Sujatha Krishnaswamy, Sampathkumar Palanisamy and Vijaya Anand Arumugam
ORCID
Author(s) ORCID Number
Vijaya Anand Arumugam http://orcid.org/0000-0001-7485-1586
Funding Agency and Grant Number
Corresponding Author Vijaya Anand Arumugam, Department of Human Genetics and Molecular Biology, Bharathiar University, Maruthamalai Road, Coimbatore 641046, Tamil Nadu, India. avahgmb@buc.edu.in
Key Words Tinospora cordifolia; Senna siamea; Quantitative analysis; Enzymatic activity; Therapeutic approach
Core Tip The following study focusses on identification of therapeutic properties of the aqueous extracts of T. cordifolia stem and S. siamea pods and leaf in leukemia cell line. Both the plants are found contain therapeutic properties and also found to be a potential treatment for ML by induction of apoptosis by increase in reactive oxygen species (ROS) activity that cause reduction in mitochondrial membrane potential (MMP). The following study is carried out in vitro and needs further clinical study to come to the conclusion.
Publish Date 2026-06-04 07:37
Citation

Boro A, Jothi Dheivasikamani A, Prabhu Jeyabal Philomenathan A, Manivannan J, Krishnaswamy S, Palanisamy S, Arumugam VA. Study of Tinospora cordifolia stem and Senna siamea leaf and pods: An in vitro therapeutic approach for leukemia. World J Biol Chem 2026; 17(2): 113144

URL https://www.wjgnet.com/1949-8454/full/v17/i2/113144.htm
DOI https://doi.org/10.4331/wjbc.v17.i2.113144
Full Article (PDF) WJBC-17-113144-with-cover.pdf
Manuscript File 113144_Auto_Edited_112545.docx
Answering Reviewers 113144-answering-reviewers.pdf
Audio Core Tip 113144-audio.m4a
Biostatistics Review Certificate 113144-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113144-conflict-of-interest-statement.pdf
Copyright License Agreement 113144-copyright-assignment.pdf
Institutional Review Board Approval Form or Document 113144-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113144-non-native-speakers.pdf
Peer-review Report 113144-peer-reviews.pdf
Scientific Misconduct Check 113144-scientific-misconduct-check.png
Scientific Editor Work List 113144-scientific-editor-work-list.pdf
CrossCheck Report 113144-crosscheck-report.pdf