BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
3/6/2026 8:56:34 AM | Browse: 3 | Download: 14
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 113155
Country Italy
Received
2025-08-18 01:53
Peer-Review Started
2025-08-18 01:53
First Decision by Editorial Office Director
2025-09-02 09:50
Return for Revision
2025-09-02 09:50
Revised
2025-09-16 17:47
Publication Fee Transferred
Second Decision by Editor
2025-12-01 02:58
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-01 08:42
Articles in Press
2025-12-01 08:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-31 13:12
Publish the Manuscript Online
2026-03-06 08:56
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Case Report
Article Title Longitudinal extensive anti-AMPA-GluR3-related transverse myelitis and favorable therapeutic response: A case report and review of literature
Manuscript Source Invited Manuscript
All Author List Maria Elena Cucuzza, Piero Pavone, Maria T Garozzo, Maria C Finocchiaro, Filippo Greco, Pierluigi Smilari, Alessandra Di Nora, Martino Ruggieri and Vita A Di Stefano
ORCID
Author(s) ORCID Number
Maria Elena Cucuzza http://orcid.org/0000-0002-2609-7141
Piero Pavone http://orcid.org/0000-0002-5600-9560
Maria C Finocchiaro http://orcid.org/0000-0003-4334-0788
Filippo Greco http://orcid.org/0000-0002-8697-6770
Martino Ruggieri http://orcid.org/0000-0002-2658-4249
Vita A Di Stefano http://orcid.org/0000-0002-7636-6557
Funding Agency and Grant Number
Corresponding Author Maria Elena Cucuzza, DM, Department of Pediatric Unit and Pediatric Emergency Room, Emergency Hospital Cannizzaro, Via Messina 829, Catania 95100, Italy. me.cucuzza@gmail.com
Key Words Longitudinal extensive transverse myelitis; Spinal cord inflammation; Immune-mediated disorder; Central nervous system; Metabotropic glutamate receptor 3 antibodies; Case report
Core Tip This case report describes a potential link between longitudinally extensive transverse myelitis (LETM) and high levels of antibodies anti metabotropic glutamate receptor 3 in a 5-year-old girl. LETM is a neurological disorder marked by a spinal cord lesion spanning three or more vertebral segments. The girl presented with lower back pain, bilateral sensory, motor impairments, and autonomic dysfunction. She had a positive response to high doses of intravenous methylprednisolone and immunoglobulin therapy. The frequency of LETM associated with antibodies anti metabotropic glutamate receptor 3 is unknown, but this case could help expand understanding of this rare condition.
Publish Date 2026-03-06 08:56
Citation

Cucuzza ME, Pavone P, Garozzo MT, Finocchiaro MC, Greco F, Smilari P, Di Nora A, Ruggieri M, Di Stefano VA. Longitudinal extensive anti-AMPA-GluR3-related transverse myelitis and favorable therapeutic response: A case report and review of literature. World J Clin Pediatr 2026; 15(1): 113155

URL https://www.wjgnet.com/2219-2808/full/v15/i1/113155.htm
DOI https://dx.doi.org/10.5409/wjcp.v15.i1.113155
Full Article (PDF) WJCP-15-113155-with-cover.pdf
CARE Checklist–2016 113155-CARE-Checklist-2016.pdf
Manuscript File 113155_Auto_Edited_082230.docx
Answering Reviewers 113155-answering-reviewers.pdf
Audio Core Tip 113155-audio.opus
Conflict-of-Interest Disclosure Form 113155-conflict-of-interest-statement.pdf
Copyright License Agreement 113155-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 113155-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 113155-non-native-speakers.pdf
Peer-review Report 113155-peer-reviews.pdf
Scientific Misconduct Check 113155-scientific-misconduct-check.png
Scientific Editor Work List 113155-scientific-editor-work-list.pdf
CrossCheck Report 113155-crosscheck-report.pdf