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1/9/2026 9:47:32 AM | Browse: 2 | Download: 12
Publication Name World Journal of Orthopedics
Manuscript ID 113228
Country India
Received
2025-08-20 05:15
Peer-Review Started
2025-08-20 05:16
First Decision by Editorial Office Director
2025-09-12 06:48
Return for Revision
2025-09-12 06:48
Revised
2025-09-25 07:05
Publication Fee Transferred
Second Decision by Editor
2025-11-12 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-12 08:03
Articles in Press
2025-11-12 08:03
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-05 01:29
Publish the Manuscript Online
2026-01-09 09:47
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell & Tissue Engineering
Manuscript Type Review
Article Title Advances in polymer-based hydrogel systems for adipose-derived mesenchymal stem cells toward bone regeneration
Manuscript Source Invited Manuscript
All Author List Nivetha Suresh, Sundaravadhanan Lekhavadhani and Nagarajan Selvamurugan
ORCID
Author(s) ORCID Number
Nagarajan Selvamurugan http://orcid.org/0000-0003-3713-1920
Funding Agency and Grant Number
Corresponding Author Nagarajan Selvamurugan, PhD, Professor, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, School of Bioengineering, Kattankulathur 603203, Tamil Nādu, India. selvamun@srmist.edu.in
Key Words Mesenchymal stem cells; Adipose-derived mesenchymal stem cells; Bone tissue engineering; Hydrogels; Bone regeneration; Polymers
Core Tip This review highlights the critical need for advanced biomaterials in bone regeneration, emphasizing hydrogels as optimized scaffolds for adipose-derived mesenchymal stem cell delivery. The innovative aspect of this study lies in its comprehensive analysis of polymer-based hydrogels synthesis, advanced embedding techniques such as three-dimensional bioprinting, and osteoinductive modifications to enhance bone regeneration. Advancements in biomaterial engineering and stem cell technology will be essential for developing effective and clinically applicable bone tissue engineering strategies. Future research should focus on addressing scalability, regulatory challenges, and long-term safety to facilitate clinical translation.
Publish Date 2026-01-09 09:47
Citation

Suresh N, Lekhavadhani S, Selvamurugan N. Advances in polymer-based hydrogel systems for adipose-derived mesenchymal stem cells toward bone regeneration. World J Orthop 2026; 17(1): 113228

URL https://www.wjgnet.com/2218-5836/full/v17/i1/113228.htm
DOI https://dx.doi.org/10.5312/wjo.v17.i1.113228
Full Article (PDF) WJO-17-113228-with-cover.pdf
Manuscript File 113228_Auto_Edited_022955.docx
Answering Reviewers 113228-answering-reviewers.pdf
Audio Core Tip 113228-audio.mp3
Conflict-of-Interest Disclosure Form 113228-conflict-of-interest-statement.pdf
Copyright License Agreement 113228-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 113228-non-native-speakers.pdf
Peer-review Report 113228-peer-reviews.pdf
Scientific Misconduct Check 113228-scientific-misconduct-check.png
Scientific Editor Work List 113228-scientific-editor-work-list.pdf
CrossCheck Report 113228-crosscheck-report.pdf