BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
1/20/2026 9:06:32 AM | Browse: 62 | Download: 183
 |
Received |
|
2025-08-20 03:05 |
|
Peer-Review Started |
|
2025-08-20 03:06 |
|
First Decision by Editorial Office Director |
|
2025-09-01 08:36 |
|
Return for Revision |
|
2025-09-01 08:36 |
|
Revised |
|
2025-09-14 03:47 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2025-11-24 02:45 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-11-25 03:24 |
|
Articles in Press |
|
2025-11-25 03:24 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-01-08 00:39 |
|
Publish the Manuscript Online |
|
2026-01-20 09:06 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medical Informatics |
| Manuscript Type |
Minireviews |
| Article Title |
Single-cell differential abundance detection: A new angle on dissecting tumor heterogeneity
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ying-Xue Xiao, Jing Sun, Ling-Ling Xie, Yue Zou, Tong Li, You-Jin Hao and Bo Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chongqing Natural Science Foundation |
CSTB2025NSCQ-GPX1031 |
|
| Corresponding Author |
Bo Li, Associate Professor, PhD, College of Life Sciences, Chongqing Normal University, No. 37 University City Middle Road, Shapingba District, Chongqing 401331, China. libcell@cqnu.edu.cn |
| Key Words |
Single-cell RNA sequencing; Tumor heterogeneity; Differential abundance detection; Tumor microenvironment; Precision oncology; Immune remodeling; Cellular composition |
| Core Tip |
This review highlights differential abundance (DA) detection as a transformative framework in single-cell oncology, enabling high-resolution deconstruction of tumor heterogeneity. It surveys widely adopted DA methods and demonstrates how capturing dynamic shifts in cellular ecosystems yields critical mechanistic insights, supports clinical decision-making, and informs precision therapeutic strategies. The ongoing methodological refinements and multi-omics convergence will further elevate DA detection to a cornerstone technology in precision oncology. |
| Publish Date |
2026-01-20 09:06 |
| Citation |
Xiao YX, Sun J, Xie LL, Zou Y, Li T, Hao YJ, Li B. Single-cell differential abundance detection: A new angle on dissecting tumor heterogeneity. World J Clin Oncol 2026; 17(1): 113244 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i1/113244.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i1.113244 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
