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Publication Name World Journal of Hepatology
Manuscript ID 113247
Country India
Received
2025-08-20 05:10
Peer-Review Started
2025-08-20 05:10
First Decision by Editorial Office Director
2025-09-01 09:08
Return for Revision
2025-09-01 09:08
Revised
2025-09-11 08:36
Publication Fee Transferred
Second Decision by Editor
2025-11-24 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-25 08:21
Articles in Press
2025-11-25 08:21
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-13 06:40
Publish the Manuscript Online
2026-01-27 10:12
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Observational Study
Article Title Uncovering silent carriers: Hematological insights and viral burden in incidentally detected hepatitis B virus infection
Manuscript Source Invited Manuscript
All Author List Manisha M Ratnaparkhi, Chanda R Vyawahare, Parag J Ratnakar, Nageswari R Gandham and Poonam V Suryawanshi
ORCID
Author(s) ORCID Number
Manisha M Ratnaparkhi http://orcid.org/0009-0008-9246-5097
Chanda R Vyawahare http://orcid.org/0000-0002-0448-3623
Parag J Ratnakar http://orcid.org/0009-0002-3225-6935
Nageswari R Gandham http://orcid.org/0000-0002-6503-0556
Poonam V Suryawanshi http://orcid.org/0000-0002-4352-5339
Funding Agency and Grant Number
Corresponding Author Chanda R Vyawahare, MD, Professor, Department of Microbiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre and Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune 411018, Mahārāshtra, India. chandavyawahare@dpu.edu.in
Key Words Hepatitis B; Hepatitis B virus deoxyribonucleic acid quantification; Hematological biomarkers; Liver function tests; Viral load; Subclinical hepatic injury
Core Tip A substantial proportion of hepatitis B virus infections remain undetected due to the asymptomatic nature of silent carriers. This study reveals that incidentally diagnosed hepatitis B surface antigen-positive individuals exhibit significant alterations in hematological and liver function parameters despite lacking clinical symptoms. Findings demonstrate a correlation between viral load and markers of hepatic injury, highlighting the need for vigilant laboratory monitoring. Early identification of subclinical liver involvement offers a critical window for intervention to prevent long-term complications such as cirrhosis and hepatocellular carcinoma. This work underscores the importance of integrating routine screening, hematological profiling, and virological assessment in public health strategies targeting hepatitis B virus control.
Publish Date 2026-01-27 10:12
Citation

Ratnaparkhi MM, Vyawahare CR, Ratnakar PJ, Gandham NR, Suryawanshi PV. Uncovering silent carriers: Hematological insights and viral burden in incidentally detected hepatitis B virus infection. World J Hepatol 2026; 18(1): 113247

URL https://www.wjgnet.com/1948-5182/full/v18/i1/113247.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i1.113247
Full Article (PDF) WJH-18-113247-with-cover.pdf
STROBE Statement 113247-STROBE-statement.pdf
Manuscript File 113247_Auto_Edited_071857.docx
Answering Reviewers 113247-answering-reviewers.pdf
Audio Core Tip 113247-audio.m4a
Biostatistics Review Certificate 113247-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113247-conflict-of-interest-statement.pdf
Copyright License Agreement 113247-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113247-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113247-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113247-non-native-speakers.pdf
Peer-review Report 113247-peer-reviews.pdf
Scientific Misconduct Check 113247-scientific-misconduct-check.png
Scientific Editor Work List 113247-scientific-editor-work-list.pdf
CrossCheck Report 113247-crosscheck-report.pdf