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12/2/2014 10:47:00 AM | Browse: 946 | Download: 1233
Publication Name World Journal of Gastroenterology
Manuscript ID 11327
Country South Korea
Received
2014-05-15 20:18
Peer-Review Started
2014-05-16 21:37
To Make the First Decision
2014-06-18 17:25
Return for Revision
2014-06-20 20:30
Revised
2014-07-08 15:54
Second Decision
2014-08-28 10:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-08-28 10:35
Articles in Press
2014-08-28 10:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-11-16 18:19
Publish the Manuscript Online
2014-12-02 10:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Topic Highlights
Article Title Recent applications of chemosensitivity tests for colorectal cancer treatment
Manuscript Source Invited Manuscript
All Author List Yong Sik Yoon and Jin Cheon Kim
Funding Agency and Grant Number
Funding Agency Grant Number
Asan Institute for Life Sciences 2014-69
National Research Foundation NRF-2013R1A2A1A03070986
Ministry of Science, ICT, and Future Planning, the Korea Health 21 RD Project HI06C0868
Ministry of Science, ICT, and Future Planning, the Korea Health 21 RD Project HI13C1750
Center for Development and Commercialization of Anti-Cancer Therapeutics HI10C2014
Corresponding Author Jin Cheon Kim, MD, PhD, Department of Surgery, University of Ulsan College of Medicine, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul 138-736, South Korea. jckim@amc.seoul.kr
Key Words Colorectal adenocarcinomas; Colorectal cancer; Chemotherapy; In vitro assays; Molecular targeted therapy; Individualized therapy
Core Tip This review summarizes currently available predictive and prognostic chemosensitivity tests and biomarkers in terms of cell culture, protein, and gene. Cell culture-based chemosensitivity tests are used widely in clinical practice because of their short assay period, technical simplicity, and the requirement of small amount of specimen. Among protein- and gene-based chemosensitivity assays, assessment of KRAS mutation status predicts the response to epidermal growth factor receptor-targeted therapy in colorectal cancer patients.
Publish Date 2014-12-02 10:46
Citation Yoon YS, Kim JC. Recent applications of chemosensitivity tests for colorectal cancer treatment. World J Gastroenterol 2014; 20(44): 16398-16408
URL http://www.wjgnet.com/1007-9327/full/v20/i44/16398.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i44.16398
Full Article (PDF) WJG-20-16398.pdf
Full Article (Word) WJG-20-16398.doc
Manuscript File 11327-Review.doc
Answering Reviewers 11327-Answering reviewers.pdf
Copyright License Agreement 11327-Copyright assignment.PDF
Non-Native Speakers of English Editing Certificate 11327-Language certificate.pdf
Peer-review Report 11327-Peer reivew.pdf
Scientific Misconduct Check 11327-CorssCheck.jpg
Scientific Editor Work List 11327-Scientific editor work list.pdf