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Articles Published Processes
12/2/2014 10:47:00 AM | Browse: 1068 | Download: 1462
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Received |
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2014-05-15 20:18 |
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Peer-Review Started |
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2014-05-16 21:37 |
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To Make the First Decision |
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2014-06-18 17:25 |
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Return for Revision |
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2014-06-20 20:30 |
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Revised |
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2014-07-08 15:54 |
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Second Decision |
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2014-08-28 10:00 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-08-28 10:35 |
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Articles in Press |
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2014-08-28 10:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-11-16 18:19 |
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Publish the Manuscript Online |
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2014-12-02 10:46 |
| Category |
Oncology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Recent applications of chemosensitivity tests for colorectal cancer treatment
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yong Sik Yoon and Jin Cheon Kim |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Asan Institute for Life Sciences |
2014-69 |
| National Research Foundation |
NRF-2013R1A2A1A03070986 |
| Ministry of Science, ICT, and Future Planning, the Korea Health 21 RD Project |
HI06C0868 |
| Ministry of Science, ICT, and Future Planning, the Korea Health 21 RD Project |
HI13C1750 |
| Center for Development and Commercialization of Anti-Cancer Therapeutics |
HI10C2014 |
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| Corresponding Author |
Jin Cheon Kim, MD, PhD, Department of Surgery, University of Ulsan College of Medicine, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul 138-736, South Korea. jckim@amc.seoul.kr |
| Key Words |
Colorectal adenocarcinomas; Colorectal cancer; Chemotherapy; In vitro assays; Molecular targeted therapy; Individualized therapy |
| Core Tip |
This review summarizes currently available predictive and prognostic chemosensitivity tests and biomarkers in terms of cell culture, protein, and gene. Cell culture-based chemosensitivity tests are used widely in clinical practice because of their short assay period, technical simplicity, and the requirement of small amount of specimen. Among protein- and gene-based chemosensitivity assays, assessment of KRAS mutation status predicts the response to epidermal growth factor receptor-targeted therapy in colorectal cancer patients. |
| Publish Date |
2014-12-02 10:46 |
| Citation |
Yoon YS, Kim JC. Recent applications of chemosensitivity tests for colorectal cancer treatment. World J Gastroenterol 2014; 20(44): 16398-16408 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i44/16398.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i44.16398 |
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