Publication Name	World Journal of Gastroenterology
Manuscript ID	11330
Country	Italy

Received	2014-05-15 20:54
Peer-Review Started	2014-05-16 22:04
To Make the First Decision	2014-06-18 17:25
Return for Revision	2014-06-20 20:31
Revised	2014-06-21 03:52
Second Decision	2014-07-30 10:08
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-07-30 10:22
Articles in Press	2014-07-30 10:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-25 10:05
Publish the Manuscript Online	2014-12-20 19:42

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Letter to the Editor
Article Title	Helicobacter, gamma-glutamyltransferase and cancer: Further intriguing connections
Manuscript Source	Unsolicited Manuscript
All Author List	Maria Franzini, Alessandro Corti, Vanna Fierabracci and Alfonso Pompella
Funding Agency and Grant Number	Funding Agency Grant Number University of Pisa School of Medicine research funds (2013)
Corresponding Author	Alfonso Pompella, MD, PhD, Professor of General Pathology, Department of Translational Research NTMC, University if Pisa Medical School, via Roma 55, 56126 Pisa, Italy. alfonso.pompella@med.unipi.it
Key Words	Helicobacter pylori; H. suis; Virulence; Gamma-glutamyltransferase; Immunosuppression; Cancer metastasis.
Core Tip	Biochemical reactions promoted by gamma-glutamyltransferase (GGT) of Helicobacter is capable of causing damage to gastric epithelium and suppression of immune response. Bacterial GGT is secreted as exosome-like vescicles, and very similar GGT-rich exosomes are released from human cancer cells. In the resistant and invasive phenotype of malignant cells, such secreted GGT may play roles akin to those described for Helicobacter infection, concurring to the establishment of cancer metastases.
Publish Date	2014-12-20 19:42
Citation	Franzini M, Corti A, Fierabracci V, Pompella A. Helicobacter, gamma-glutamyltransferase and cancer: Further intriguing connections. World J Gastroenterol 2014; 20(47): 18057-18058
URL	http://www.wjgnet.com/1007-9327/full/v20/i47/18057.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i47.18057

Full Article (PDF)	WJG-20-18057.pdf
Full Article (Word)	WJG-20-18057.doc
Manuscript File	11330-Review.doc
Answering Reviewers	11330-Answering reviewers.pdf
Copyright License Agreement	11330-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	11330-Language certificate.pdf
Peer-review Report	11330-Peer review.pdf
Scientific Misconduct Check	11330-CorssCheck.jpg
Scientific Editor Work List	11330-Scientific editor work list.pdf