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Articles Published Processes
3/23/2026 8:21:09 AM | Browse: 0 | Download: 0
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Received |
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2025-08-22 08:30 |
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Peer-Review Started |
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2025-08-22 08:30 |
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First Decision by Editorial Office Director |
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2025-09-16 09:48 |
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Return for Revision |
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2025-09-16 09:48 |
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Revised |
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2025-09-25 12:23 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-23 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-23 07:12 |
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Articles in Press |
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2026-01-23 07:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-27 08:39 |
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Publish the Manuscript Online |
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2026-03-23 08:21 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Endothelial metabolic reprogramming influences tumor immune microenvironment
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ming Chen and Zhi-Gang Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81972598, 82273337 |
| National Key R&D Program |
2022YFA1105201 |
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| Corresponding Author |
Zhi-Gang Chen, Chief, MD, PhD, Professor, Department of Breast Surgery (Surgical Oncology), Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 310000, Zhejiang Province, China. chenzhigang@zju.edu.cn |
| Key Words |
Tumor microenvironment; Tumor endothelial cells; Metabolic reprogramming; Immunosuppression; Immunotherapy |
| Core Tip |
In recent years, the tumor microenvironment (TME) has emerged as a critical target in cancer research due to its role in regulating tumor growth, metastasis and treatment response. Immune cells are core components of the TME, and the effects of tumor cell metabolic reprogramming on immune cells are well understood. However, research on the impact of metabolic reprogramming of tumor endothelial cells on the tumor immune microenvironment is limited. This review summarizes metabolic changes in endothelial cells within the TME and their effects on the tumor immune microenvironment. It also suggests combining anti-angiogenic therapy that targets endothelial metabolism with immunotherapy as a future treatment option. |
| Publish Date |
2026-03-23 08:21 |
| Citation |
Chen M, Chen ZG. Endothelial metabolic reprogramming influences tumor immune microenvironment. World J Clin Oncol 2026; 17(3): 113326 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i3/113326.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i3.113326 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
