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12/11/2025 8:20:57 AM | Browse: 3 | Download: 1
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 113341
Country Saudi Arabia
Received
2025-08-22 10:08
Peer-Review Started
2025-08-22 10:08
First Decision by Editorial Office Director
2025-09-12 05:35
Return for Revision
2025-09-12 05:35
Revised
2025-09-22 14:04
Publication Fee Transferred
2025-09-23 06:09
Second Decision by Editor
2025-10-13 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-13 08:13
Articles in Press
2025-10-13 08:13
Edit the Manuscript by Language Editor
2025-10-18 22:39
Typeset the Manuscript
2025-11-25 07:35
Publish the Manuscript Online
2025-12-11 08:20
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Tumor calcification and sustained complete response after chemoembolization in hepatocellular carcinoma: Two case reports and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Sultan R Alharbi
ORCID
Author(s) ORCID Number
Sultan R Alharbi http://orcid.org/0000-0001-7369-9869
Funding Agency and Grant Number
Corresponding Author Sultan R Alharbi, Associate Professor, MD, Interventional Radiology Unit/Department of Radiology and medical imaging, College of Medicine, King Saud University, PO Box 7805, King Abdullah Street, Riyadh 11362, Saudi Arabia. drsultan000@gmail.com
Key Words Hepatocellular carcinoma; Transarterial chemoembolization; Drug eluting beads chemoembolization; Complete response; Remission; Tumoral calcification; Case report
Core Tip Tumoral calcification following transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) is a rare imaging finding, and its clinical significance remains unclear. This case report describes two patients with large HCC who developed complete radiological response after drug-eluting beads TACE, followed by progressive peripheral calcification and sustained disease-free survival for 6 years. The notable association between post-TACE calcification and long-term remission raises the possibility that calcification may serve as a late imaging biomarker of effective tumor necrosis and durable treatment response.
Publish Date 2025-12-11 08:20
Citation

Alharbi SR. Tumor calcification and sustained complete response after chemoembolization in hepatocellular carcinoma: Two case reports and review of literature. World J Gastrointest Oncol 2025; 17(12): 113341

URL https://www.wjgnet.com/1948-5204/full/v17/i12/113341.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i12.113341
Full Article (PDF) WJGO-17-113341-with-cover.pdf
CARE Checklist–2016 113341-CARE-Checklist-2016.pdf
Manuscript File 113341_Auto_Edited_030154.docx
Answering Reviewers 113341-answering-reviewers.pdf
Audio Core Tip 113341-audio.m4a
Conflict-of-Interest Disclosure Form 113341-conflict-of-interest-statement.pdf
Copyright License Agreement 113341-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 113341-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 113341-non-native-speakers.pdf
Peer-review Report 113341-peer-reviews.pdf
Scientific Misconduct Check 113341-scientific-misconduct-check.png
Scientific Editor Work List 113341-scientific-editor-work-list.pdf
CrossCheck Report 113341-crosscheck-report.pdf