| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Safety and efficacy of cryoablation in treating locally advanced pancreatic cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Min Kang, Xiao-Long He, Li Lang, A-Yong Wang, Xian Wang, Yu-Hao Liu, Ying-Hong Zhao, Lei Xu, Fa-Kun Yu and Fu-Wei Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Li-Min Kang, MD, PhD, Professor, Department of Hepatobiliary and Pancreatic Surgery, Puer People’s Hospital, No. 44 Zhenxing Street, Puer 665000, Yunnan Province, China. kanglimin2010@163.com |
| Key Words |
Pancreatic cancer; Cryoablation; Ultrasound guidance; Complication; Postoperative follow-up |
| Core Tip |
Pancreatic cancer has an extremely poor prognosis. In particular, chemotherapy, targeted therapy, and immunotherapy may be ineffective for locally advanced pancreatic cancer (LAPC) because of its resistance to these modalities. In this retrospective study, 24 LAPC patients were treated with cryoablation at our hospital. The outcomes show that cryoablation can directly inactivate LAPC and boost immunity, thus delaying tumor progression, alleviating pain, improving quality of life, and prolonging survivals. Therefore, it is a safe and effective treatment option for LAPC that deserves wider adoption in clinical settings. |
| Publish Date |
2025-12-11 08:20 |
| Citation |
Kang LM, He XL, Lang L, Wang AY, Wang X, Liu YH, Zhao YH, Xu L, Yu FK, Zhang FW. Safety and efficacy of cryoablation in treating locally advanced pancreatic cancer. World J Gastrointest Oncol 2025; 17(12): 113387 |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i12/113387.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i12.113387 |