Publication Name	World Journal of Clinical Oncology
Manuscript ID	11340
Country	Japan

Received	2014-05-19 11:06
Peer-Review Started	2014-05-20 08:26
To Make the First Decision	2014-06-06 11:02
Return for Revision	2014-06-16 11:01
Revised	2014-06-23 07:04
Second Decision	2014-09-10 13:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-09-10 14:00
Articles in Press	2014-09-10 14:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-18 09:09
Publish the Manuscript Online	2014-12-11 14:23

ISSN	2218-4333 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Estrogen receptors as the novel therapeutic biomarker in non-small cell lung cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Hideki Kawai
Funding Agency and Grant Number
Corresponding Author	Hideki Kawai, MD, PhD, Department of Thoracic Surgery, Akita Red Cross Hospital, 222-1 Naeshirosawa, Saruta, Kamikitate, Akita 010-1495, Japan. kawai-h@akita-rch.com
Key Words	Estrogen receptor; Non-small cell lung cancer; Epidermal growth factor receptor; Fulvestrant; Combined therapy
Core Tip	Although there were many studies regarding the role of estrogen receptor (ER) in non-small cell lung cancer (NSCLC), the rate of ER expression or the intracellular distribution of ER remains controversial. This suggests that establishing the relationship between ER expression and prognosis will require standardization of the antibodies used as well as the definition of a positive response. Furthermore, there has been little functional analysis for ER variants. This review will focus on what is known about the role of ERs in NSCLC and whether ER can be a useful prognostic marker or therapeutic target in NSCLC.
Publish Date	2014-12-11 14:23
Citation	Kawai H. Estrogen receptors as the novel therapeutic biomarker in non-small cell lung cancer. World J Clin Oncol 2014; 5(5): 1020-1027
URL	http://www.wjgnet.com/2218-4333/full/v5/i5/1020.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i5.1020

Full Article (PDF)	WJCO-5-1020.pdf
Full Article (Word)	WJCO-5-1020.doc
Manuscript File	11340-Review.docx
Answering Reviewers	11340-Answering reviewers.pdf
Copyright License Agreement	11340-Copyright assignment.pdf
Peer-review Report	11340-Peer review(s).pdf
Scientific Misconduct Check	11340-CrossCheck.jpg
Scientific Editor Work List	11340-Scientific editor work list.pdf