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Articles Published Processes
1/12/2026 9:50:47 AM | Browse: 1 | Download: 11
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Received |
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2025-08-26 02:54 |
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Peer-Review Started |
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2025-08-26 02:54 |
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First Decision by Editorial Office Director |
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2025-09-28 10:48 |
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Return for Revision |
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2025-09-28 10:48 |
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Revised |
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2025-10-09 14:21 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-24 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-24 08:03 |
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Articles in Press |
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2025-11-24 08:03 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-29 09:10 |
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Publish the Manuscript Online |
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2026-01-12 09:50 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Beyond rheumatology: Reconsidering methotrexate for Crohn’s disease in the biologic era
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jun-Young Seo and Jun Hwan Yoo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jun Hwan Yoo, Associate Professor, MD, PhD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, 59 Yatap-ro, Bundang-gu, Seongnam-si 13496, South Korea. jhyoo@cha.ac.kr |
| Key Words |
Methotrexate; Crohn’s disease; Biologics; Immunosuppressants; Clinical practice |
| Core Tip |
Methotrexate remains underutilized in Crohn’s disease management despite its favorable safety and established efficacy. The nationwide French survey by Bonnaud et al has shown that barriers are less about evidence than about clinical inertia and limited familiarity. Reconsidering methotrexate as a frontline immunomodulator, particularly in the biologic era, may provide a cost-effective and individualized therapeutic strategy. |
| Publish Date |
2026-01-12 09:50 |
| Citation |
Seo JY, Yoo JH. Beyond rheumatology: Reconsidering methotrexate for Crohn’s disease in the biologic era. World J Gastroenterol 2026; 32(2): 113432 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i2/113432.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i2.113432 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
