BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
1/16/2026 11:31:18 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 113452
Country South Korea
Received
2025-08-26 04:52
Peer-Review Started
2025-08-26 04:52
First Decision by Editorial Office Director
2025-10-21 09:18
Return for Revision
2025-10-21 09:18
Revised
2025-10-23 14:10
Publication Fee Transferred
2025-10-28 03:51
Second Decision by Editor
2025-12-05 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-05 07:33
Articles in Press
2025-12-05 07:33
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-31 09:11
Publish the Manuscript Online
2026-01-16 11:31
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Is salvage treatment necessary after incomplete resection of rectal neuroendocrine tumors: A systematic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Jae Hyun Kim, Jung Won Lee, Hyun Jung Kim, Seung Min Hong and Seun Ja Park
ORCID
Author(s) ORCID Number
Jae Hyun Kim http://orcid.org/0000-0002-4272-8003
Jung Won Lee http://orcid.org/0000-0002-7945-1618
Hyun Jung Kim http://orcid.org/0000-0003-2018-2385
Seun Ja Park http://orcid.org/0000-0003-3217-5155
Funding Agency and Grant Number
Corresponding Author Seun Ja Park, Chairman, MD, PhD, Professor, Department of Internal Medicine, Kosin University College of Medicine, Gamcheonro 262, Seogu, Busan 49267, South Korea. parksj6406@daum.net
Key Words Rectum; Neuroendocrine tumors; Residual neoplasm; Salvage therapy; Observation
Core Tip Incomplete resection of rectal neuroendocrine tumors raises concern for residual disease and recurrence, yet the optimal management remains debated. In this systematic review and meta-analysis of 34 studies, residual tumors were identified on salvage pathology in about 25% of cases, whereas recurrence was rare in both salvage and observation groups. Although crude data suggested fewer recurrences with salvage treatment, comparative meta-analysis showed no significant difference. These findings highlight salvage resection as a diagnostic and therapeutic option, but its routine use for recurrence prevention is uncertain. Clinical decisions should be individualized.
Publish Date 2026-01-16 11:31
Citation

Kim JH, Lee JW, Kim HJ, Hong SM, Park SJ. Is salvage treatment necessary after incomplete resection of rectal neuroendocrine tumors: A systematic review and meta-analysis. World J Gastroenterol 2026; 32(3): 113452

URL https://www.wjgnet.com/1007-9327/full/v32/i3/113452.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i3.113452
Full Article (PDF) WJG-32-113452-with-cover.pdf
PRISMA 2009 Checklist 113452-PRISMA-2009-Checklist.pdf
Manuscript File 113452_Auto_Edited_023231.docx
Answering Reviewers 113452-answering-reviewers.pdf
Audio Core Tip 113452-audio.m4a
Biostatistics Review Certificate 113452-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113452-conflict-of-interest-statement.pdf
Copyright License Agreement 113452-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 113452-non-native-speakers.pdf
Supplementary Material 113452-supplementary-material.pdf
Peer-review Report 113452-peer-reviews.pdf
Scientific Misconduct Check 113452-scientific-misconduct-check.png
Scientific Editor Work List 113452-scientific-editor-work-list.pdf
CrossCheck Report 113452-crosscheck-report.pdf