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4/21/2026 8:57:43 AM | Browse: 1 | Download: 1
Publication Name World Journal of Hepatology
Manuscript ID 113458
Country Brazil
Received
2025-08-26 03:28
Peer-Review Started
2025-08-26 03:28
First Decision by Editorial Office Director
2025-09-20 02:07
Return for Revision
2025-09-20 02:07
Revised
2025-12-17 03:58
Publication Fee Transferred
Second Decision by Editor
2026-02-10 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-10 08:58
Articles in Press
2026-02-10 08:58
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-10 06:24
Publish the Manuscript Online
2026-04-21 08:57
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Poor performance of strength, assistance with walking, rising from a chair, climbing stairs and falls for sarcopenia screening in cirrhosis: A pilot study
Manuscript Source Invited Manuscript
All Author List Bruna Goularth Lacerda, Luis F Ferreira, Lilian Kethelyn Teixeira Pinheiro, Claudio A Marroni and Sabrina Alves Fernandes
ORCID
Author(s) ORCID Number
Luis F Ferreira http://orcid.org/0000-0002-9496-4884
Claudio A Marroni http://orcid.org/0000-0002-1718-6548
Sabrina Alves Fernandes http://orcid.org/0000-0001-8504-603X
Funding Agency and Grant Number
Corresponding Author Sabrina Alves Fernandes, PhD, Researcher, Program in Hepatology, Universidade Federal de Ciências da Saúde de Porto Alegre, Sarmento Leite 245, Porto Alegre 90050-170, Rio Grande do Sul, Brazil. sabrinaafernandes@gmail.com
Key Words Liver cirrhosis; Sarcopenia; Nutritional status; Screening instruments; Hand strength
Core Tip Sarcopenia is common in cirrhosis and negatively affects prognosis. Early detection is essential for effective management. We evaluated the strength, assistance with walking, rising from a chair, climbing stairs and falls (SARC-F) questionnaire as a screening tool in 45 cirrhotic patients. We compared its performance with objective functional tests, including handgrip strength and the Five times sit-to-stand test. Our main finding is that SARC-F significantly underperformed, missing all true positive cases and showing low sensitivity. In contrast, functional tests detected more patients at risk and proved more reliable. This indicates that SARC-F should not be used alone in cirrhotic patients. Functional assessments provide better guidance and should be integrated into clinical screening protocols.
Publish Date 2026-04-21 08:57
Citation

Lacerda BG, Ferreira LF, Pinheiro LKT, Marroni CA, Fernandes SA. Poor performance of strength, assistance with walking, rising from a chair, climbing stairs and falls for sarcopenia screening in cirrhosis: A pilot study. World J Hepatol 2026; 18(4): 113458

URL https://www.wjgnet.com/1948-5182/full/v18/i4/113458.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i4.113458
Full Article (PDF) WJH-18-113458-with-cover.pdf
STROBE Statement 113458-STROBE-statement.pdf
Manuscript File 113458_Auto_Edited_065314.docx
Answering Reviewers 113458-answering-reviewers.pdf
Audio Core Tip 113458-audio.mp3
Biostatistics Review Certificate 113458-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113458-conflict-of-interest-statement.pdf
Copyright License Agreement 113458-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113458-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113458-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113458-non-native-speakers.pdf
Peer-review Report 113458-peer-reviews.pdf
Scientific Misconduct Check 113458-scientific-misconduct-check.png
Scientific Editor Work List 113458-scientific-editor-work-list.pdf
CrossCheck Report 113458-crosscheck-report.pdf