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1/20/2026 9:06:34 AM | Browse: 2 | Download: 0
Publication Name World Journal of Clinical Oncology
Manuscript ID 113463
Country Israel
Received
2025-08-26 04:50
Peer-Review Started
2025-08-26 04:50
First Decision by Editorial Office Director
2025-09-04 07:19
Return for Revision
2025-09-04 07:19
Revised
2025-09-15 15:19
Publication Fee Transferred
2025-11-20 11:44
Second Decision by Editor
2025-12-23 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-23 07:55
Articles in Press
2025-12-23 07:55
Edit the Manuscript by Language Editor
2025-12-27 22:42
Typeset the Manuscript
2026-01-08 00:37
Publish the Manuscript Online
2026-01-20 09:06
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Patients’ perception of proton pump inhibitors use and their risks
Manuscript Source Unsolicited Manuscript
All Author List Ibrahim O Sawaied, Abraham O Samson and Efrat Golan
ORCID
Author(s) ORCID Number
Ibrahim O Sawaied http://orcid.org/0009-0009-1312-9579
Funding Agency and Grant Number
Corresponding Author Ibrahim O Sawaied, Azrieli Faculty of Medicine, Bar Ilan University, Henrietta Szold St 8, Safed 2170000, Israel. ibomsa13@gmail.com
Key Words Proton pump inhibitors; Gastric cancer; Patient awareness; Adverse effects; Clinical practice; Deprescribing
Core Tip This study is among the largest cross-sectional surveys of proton pump inhibitor users, involving 3000 patients across Israel. We found that most patients are unaware of the risks associated with long-term proton pump inhibitor therapy, including the potential link to gastric cancer. Despite lansoprazole showing a safer profile and greater improvements in quality of life, it remains underutilized compared with omeprazole and esomeprazole. Family support emerged as a protective factor, encouraging deprescribing attempts and improving patient outcomes. These findings highlight the need for better patient education, risk communication, and alignment of prescribing practices with current clinical evidence.
Publish Date 2026-01-20 09:06
Citation

Sawaied IO, Samson AO, Golan E. Patients’ perception of proton pump inhibitors use and their risks. World J Clin Oncol 2026; 17(1): 113463

URL https://www.wjgnet.com/2218-4333/full/v17/i1/113463.htm
DOI https://dx.doi.org/10.5306/wjco.v17.i1.113463
Full Article (PDF) WJCO-17-113463-with-cover.pdf
STROBE Statement 113463-STROBE-statement.pdf
Manuscript File 113463_Auto_Edited_114418.docx
Answering Reviewers 113463-answering-reviewers.pdf
Audio Core Tip 113463-audio.opus
Biostatistics Review Certificate 113463-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113463-conflict-of-interest-statement.pdf
Copyright License Agreement 113463-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113463-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113463-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113463-non-native-speakers.pdf
Peer-review Report 113463-peer-reviews.pdf
Scientific Misconduct Check 113463-scientific-misconduct-check.png
Scientific Editor Work List 113463-scientific-editor-work-list.pdf
CrossCheck Report 113463-crosscheck-report.pdf