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Articles Published Processes
1/27/2026 10:12:32 AM | Browse: 0 | Download: 0
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Received |
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2025-08-27 23:19 |
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Peer-Review Started |
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2025-08-27 23:20 |
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First Decision by Editorial Office Director |
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2025-09-03 06:46 |
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Return for Revision |
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2025-09-03 06:46 |
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Revised |
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2025-09-16 16:25 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-04 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-04 06:30 |
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Articles in Press |
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2025-12-04 06:30 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-13 06:42 |
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Publish the Manuscript Online |
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2026-01-27 10:12 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Blood markers vs transient elastography for liver stiffness and steatosis in metabolic dysfunction-associated steatotic liver disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Amal Joseph, Sunil Mathew and Harikumar R Nair |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Harikumar R Nair, Consultant, FRCP, MRCP, Department of Gastroenterology and Hepatology, Ernakulam Medical Centre, National Highway Bypass, NH 66, Palarivattom, Kochi 682028, Kerala, India. harikumnair@yahoo.co.in |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Non-alcoholic fatty liver disease; Transient elastography; Fibrosis-4 index; Aspartate transaminase to platelet ratio index; Neutrophil percentage to albumin ratio; Liver stiffness; Steatosis; Fibrosis |
| Core Tip |
This study demonstrates that blood-based markers are cost-effective adjuvants to FibroScan for metabolic dysfunction-associated steatotic liver disease (MASLD) assessment. Fibrosis 4 and aspartate transaminase to platelet ratio index demonstrated strong correlations with liver stiffness measurement (LSM), confirming their reliability for fibrosis evaluation. Notably, neutrophil percentage-to-albumin ratio emerged as a novel marker with a specificity (97.67%) for steatosis assessment, while platelet-to-lymphocyte ratio showed an inverse correlation with LSM. These findings support integrating simple blood markers with imaging techniques for enhanced diagnostic precision, particularly valuable in primary care settings where repeated FibroScan measurements are financially or logistically challenging, addressing critical gaps in MASLD management. |
| Publish Date |
2026-01-27 10:12 |
| Citation |
Joseph A, Mathew S, Nair HR. Blood markers vs transient elastography for liver stiffness and steatosis in metabolic dysfunction-associated steatotic liver disease. World J Hepatol 2026; 18(1): 113475 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i1/113475.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i1.113475 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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