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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 113518
Country China
Received
2025-09-16 09:31
Peer-Review Started
2025-09-16 09:31
First Decision by Editorial Office Director
2025-10-10 02:29
Return for Revision
2025-10-10 02:29
Revised
2025-10-20 14:57
Publication Fee Transferred
2025-10-22 03:14
Second Decision by Editor
2025-11-28 03:01
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-28 05:58
Articles in Press
2025-11-28 05:58
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-12 07:28
Publish the Manuscript Online
2026-01-21 09:49
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Patterns and risk factors of early recurrence after radical resection for intrahepatic cholangiocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Chen-Yang Zhou, Jing-Yuan Chen, Dan Wang, Shu Zhu and Hong-Chang Luo
ORCID
Author(s) ORCID Number
Chen-Yang Zhou http://orcid.org/0000-0001-6135-9293
Hong-Chang Luo http://orcid.org/0009-0003-4940-1112
Funding Agency and Grant Number
Corresponding Author Hong-Chang Luo, Associate Chief Physician, MD, Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Qiaokou District, Wuhan 430030, Hubei Province, China. m18730873442@163.com
Key Words Intrahepatic cholangiocarcinoma; Early recurrence; Radical resection; Risk factors; Prognosis; Survival
Core Tip Intrahepatic cholangiocarcinoma demonstrates substantial susceptibility to early postoperative recurrence, which profoundly compromises clinical prognosis. Within this extensive retrospective investigation involving 386 participants, 46.1% manifested early disease recurrence during the initial 12 postoperative months, exhibiting a median overall survival duration of merely 18.5 months. Six autonomous predictive indicators were determined: Neoplasm diameter exceeding 5 cm, multiple lesions, metastatic lymph node involvement, microscopic vascular invasion, carbohydrate antigen 19-9 exceeding 200 U/mL, and R1 resection status. An innovative risk assessment framework successfully stratified individuals into low-, intermediate-, and high-risk categories, facilitating personalized surveillance protocols and adjuvant treatment strategies to optimize postoperative outcomes in intrahepatic cholangiocarcinoma management.
Publish Date 2026-01-21 09:49
Citation

Zhou CY, Chen JY, Wang D, Zhu S, Luo HC. Patterns and risk factors of early recurrence after radical resection for intrahepatic cholangiocarcinoma. World J Gastrointest Surg 2026; 18(1): 113518

URL https://www.wjgnet.com/1948-9366/full/v18/i1/113518.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i1.113518
Full Article (PDF) WJGS-18-113518-with-cover.pdf
Manuscript File 113518_Auto_Edited_073027.docx
Answering Reviewers 113518-answering-reviewers.pdf
Audio Core Tip 113518-audio.mp3
Biostatistics Review Certificate 113518-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113518-conflict-of-interest-statement.pdf
Copyright License Agreement 113518-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113518-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113518-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113518-non-native-speakers.pdf
Peer-review Report 113518-peer-reviews.pdf
Scientific Misconduct Check 113518-scientific-misconduct-check.png
Scientific Editor Work List 113518-scientific-editor-work-list.pdf
CrossCheck Report 113518-crosscheck-report.pdf