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2/26/2026 10:19:31 AM | Browse: 4 | Download: 1
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 113525
Country China
Received
2025-09-12 08:26
Peer-Review Started
2025-09-12 08:26
First Decision by Editorial Office Director
2025-10-10 02:27
Return for Revision
2025-10-10 02:27
Revised
2025-10-24 08:00
Publication Fee Transferred
2025-10-28 06:53
Second Decision by Editor
2025-12-08 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-08 04:29
Articles in Press
2025-12-08 04:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-05 01:07
Publish the Manuscript Online
2026-02-26 10:19
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Retrospective Study
Article Title Impact of dexmedetomidine preconditioning on analgesic and postoperative recovery in elderly patients undergoing laparoscopic cholecystectomy
Manuscript Source Unsolicited Manuscript
All Author List Min Chen, Fang-Ci Chen, Qin Pan and Zhao-Hui Liu
ORCID
Author(s) ORCID Number
Zhao-Hui Liu http://orcid.org/0009-0003-2323-0191
Funding Agency and Grant Number
Corresponding Author Zhao-Hui Liu, Associate Chief Physician, Department of Colorectal Surgery, The First People's Hospital of Linping District Hangzhou City, No. 369 Yingbin Road, Nanyuan Subdistrict, Hangzhou 311199, Zhejiang Province, China. 15397152776@139.com
Key Words Dexmedetomidine; Preconditioning anesthesia; Laparoscopic cholecystectomy; Elderly patients; Postoperative pain; Recovery
Core Tip This study demonstrates that administering a loading dose of dexmedetomidine (DEX) as a pre-treatment strategy before anesthesia induction offers notable benefits for elderly patients undergoing laparoscopic cholecystectomy. Compared to the routine use of DEX solely during surgery, pre-treatment with DEX enhanced postoperative analgesia, reduced oxidative stress and inflammation, accelerated recovery of gastrointestinal and cognitive functions, and lowered the incidence of agitation without increasing intraoperative hemodynamic risks. These findings highlight the critical importance of the timing of DEX administration and suggest a promising optimized anesthesia approach to promote recovery in elderly surgical patients.
Publish Date 2026-02-26 10:19
Citation

Chen M, Chen FC, Pan Q, Liu ZH. Impact of dexmedetomidine preconditioning on analgesic and postoperative recovery in elderly patients undergoing laparoscopic cholecystectomy. World J Gastrointest Surg 2026; 18(2): 113525

URL https://www.wjgnet.com/1948-9366/full/v18/i2/113525.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i2.113525
Full Article (PDF) WJGS-18-113525-with-cover.pdf
Manuscript File 113525_Auto_Edited_021618.docx
Answering Reviewers 113525-answering-reviewers.pdf
Audio Core Tip 113525-audio.mp3
Biostatistics Review Certificate 113525-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113525-conflict-of-interest-statement.pdf
Copyright License Agreement 113525-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113525-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113525-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113525-non-native-speakers.pdf
Peer-review Report 113525-peer-reviews.png
Peer-review Report 113525-peer-reviews.pdf
Scientific Editor Work List 113525-scientific-editor-work-list.pdf
CrossCheck Report 113525-crosscheck-report.pdf