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12/10/2025 7:48:09 AM | Browse: 3 | Download: 3
Publication Name World Journal of Gastroenterology
Manuscript ID 113528
Country China
Received
2025-08-27 23:10
Peer-Review Started
2025-08-27 23:11
First Decision by Editorial Office Director
2025-09-20 02:27
Return for Revision
2025-09-20 02:27
Revised
2025-10-02 20:34
Publication Fee Transferred
Second Decision by Editor
2025-11-04 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-04 08:39
Articles in Press
2025-11-04 08:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-04 06:50
Publish the Manuscript Online
2025-12-10 07:48
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Health Care Sciences & Services
Manuscript Type Letter to the Editor
Article Title Additional considerations on vonoprazan triple therapy for Helicobacter pylori eradication: Implementation challenges and clinical perspectives
Manuscript Source Unsolicited Manuscript
All Author List Chu-Ying Sun and Ming-Xian Chen
ORCID
Author(s) ORCID Number
Ming-Xian Chen http://orcid.org/0000-0003-2944-6850
Funding Agency and Grant Number
Corresponding Author Ming-Xian Chen, Chief Physician, MD, Professor, Department of Gastroenterology, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou 310012, Zhejiang Province, China. chenmingxian2005@126.com
Key Words Helicobacter pylori; Vonoprazan; Multicenter trial; Regional differences; Clinical implementation
Core Tip Han et al’s multicenter trial demonstrates vonoprazan triple therapy’s superior efficacy over standard bismuth quadruple therapy for Helicobacter pylori eradication in China, successful nationwide implementation faces critical challenges. Key barriers include limited drug accessibility in primary healthcare settings, higher costs compared to traditional therapies, and significant regional variations in antibiotic resistance patterns across China’s diverse population. The study’s single-province design cannot fully represent national applicability. Addressing these implementation gaps through comprehensive health system research, cost-effectiveness analyses, and multi-regional validation studies is essential for translating these promising clinical findings into improved patient outcomes across China’s heterogeneous healthcare landscape.
Publish Date 2025-12-10 07:48
Citation

Sun CY, Chen MX. Additional considerations on vonoprazan triple therapy for Helicobacter pylori eradication: Implementation challenges and clinical perspectives. World J Gastroenterol 2025; 31(46): 113528

URL https://www.wjgnet.com/1007-9327/full/v31/i46/113528.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i46.113528
Full Article (PDF) WJG-31-113528-with-cover.pdf
Manuscript File 113528_Auto_Edited_020639.docx
Answering Reviewers 113528-answering-reviewers.pdf
Audio Core Tip 113528-audio.m4a
Conflict-of-Interest Disclosure Form 113528-conflict-of-interest-statement.pdf
Copyright License Agreement 113528-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 113528-non-native-speakers.pdf
Peer-review Report 113528-peer-reviews.pdf
Scientific Misconduct Check 113528-scientific-misconduct-check.png
Scientific Editor Work List 113528-scientific-editor-work-list.pdf
CrossCheck Report 113528-crosscheck-report.pdf