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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 113553
Country Mexico
Received
2025-09-02 04:47
Peer-Review Started
2025-09-02 04:48
First Decision by Editorial Office Director
2025-09-09 09:27
Return for Revision
2025-09-09 09:27
Revised
2025-09-30 03:01
Publication Fee Transferred
Second Decision by Editor
2025-11-18 01:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-18 08:29
Articles in Press
2025-11-18 08:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-04 01:02
Publish the Manuscript Online
2026-01-12 10:07
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Tumor microenvironment-driven microRNA dysregulation: Key interactions in colorectal cancer progression
Manuscript Source Invited Manuscript
All Author List Adriana G Quiroz-Reyes, Paulina Delgado-Gonzalez, Jose Francisco Islas, Veronica L Loaiza-Gutierrez, Michelle G Santoyo-Suarez, Juan A Garcia-Loredo, Carlos A Gonzalez-Villarreal, Fernanda Ramirez-Fernandez and Elsa N Garza-Treviño
ORCID
Author(s) ORCID Number
Adriana G Quiroz-Reyes http://orcid.org/0000-0002-9405-7483
Paulina Delgado-Gonzalez http://orcid.org/0000-0002-0492-7968
Jose Francisco Islas http://orcid.org/0000-0002-0337-9912
Veronica L Loaiza-Gutierrez http://orcid.org/0009-0005-5057-9326
Michelle G Santoyo-Suarez http://orcid.org/0000-0001-5957-6475
Carlos A Gonzalez-Villarreal http://orcid.org/0000-0002-4890-1727
Elsa N Garza-Treviño http://orcid.org/0000-0002-1042-4603
Funding Agency and Grant Number
Corresponding Author Elsa N Garza-Treviño, Affiliate Associate Professor, Associate Professor, Department of Biochemistry and Molecular Medicine, Universidad Autonoma de Nuevo Leon, Av. Francisco I Madero Pte. s/n y Calle Dr. Eduardo Aguirre Pequeño. Colonia Mitras Centro, Monterrey 64460, Nuevo Leon, Mexico. elsa.garzatr@uanl.edu.mx
Key Words Cancer progression; MicroRNAs; Colorectal cancer; Tumor microenvironment; Therapeutic response
Core Tip MicroRNAs are crucial regulators of colorectal cancer progression, influencing tumor development, therapeutic response, and serving as potential biomarkers or therapeutic targets. Their expression is strongly shaped by the dynamic interaction between tumor cells and the tumor microenvironment. This comprehensive review summarizes the key microRNAs implicated in tumor progression and discusses the main therapeutic targets, highlighting current knowledge and strategies designed to modulate their expression and enhance treatment response.
Publish Date 2026-01-12 10:07
Citation

Quiroz-Reyes AG, Delgado-Gonzalez P, Islas JF, Loaiza-Gutierrez VL, Santoyo-Suarez MG, Garcia-Loredo JA, Gonzalez-Villarreal CA, Ramirez-Fernandez F, Garza-Treviño EN. Tumor microenvironment-driven microRNA dysregulation: Key interactions in colorectal cancer progression. World J Gastrointest Oncol 2026; 18(1): 113553

URL https://www.wjgnet.com/1948-5204/full/v18/i1/113553.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i1.113553
Full Article (PDF) WJGO-18-113553-with-cover.pdf
Manuscript File 113553_Auto_Edited_064710.docx
Answering Reviewers 113553-answering-reviewers.pdf
Audio Core Tip 113553-audio.m4a
Conflict-of-Interest Disclosure Form 113553-conflict-of-interest-statement.pdf
Copyright License Agreement 113553-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 113553-non-native-speakers.pdf
Peer-review Report 113553-peer-reviews.pdf
Scientific Misconduct Check 113553-scientific-misconduct-check.png
Scientific Editor Work List 113553-scientific-editor-work-list.pdf
CrossCheck Report 113553-crosscheck-report.pdf