Publication Name	World Journal of Clinical Cases
Manuscript ID	113560
Country	Japan

Received	2025-08-29 05:36
Peer-Review Started	2025-08-29 05:36
To Make the First Decision
Return for Revision	2025-09-12 06:32
Revised	2025-09-25 08:34
Second Decision	2025-11-05 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-05 05:49
Articles in Press	2025-11-05 05:49
Publication Fee Transferred	2025-09-26 05:24
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-11-14 00:21
Publish the Manuscript Online	2025-11-21 03:54

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Toxicology
Manuscript Type	Case Report
Article Title	Severe venlafaxine poisoning successfully rescued with veno-arterial extracorporeal membrane oxygenation: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Kurumi Mori, Yoshito Kamijo, Tomoki Doi, Hiroko Abe and Ichiro Takeuchi
ORCID	Author(s) ORCID Number Kurumi Mori http://orcid.org/0009-0000-3745-0636
Funding Agency and Grant Number
Corresponding Author	Kurumi Mori, Department of Emergency and Critical Care Medicine, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, Kanagawa, Japan. e123082b@yokohama-cu.ac.jp
Key Words	Venlafaxine; Massive ingestion; QTc prolongation; Veno-arterial extracorporeal membrane oxygenation; Ventricular fibrillation; Case report
Core Tip	A 31-year-old woman ingested a massive dose of venlafaxine (14.8 g) and initially showed only mild QTc prolongation. However, she developed ventricular fibrillation 15 hours post-ingestion. She was successfully managed with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This case highlights the potential for delayed but life-threatening cardiotoxicity in venlafaxine overdose and demonstrates the utility of VA-ECMO as a life-saving intervention. Continuous electrocardiographic monitoring beyond the early phase is essential even when initial findings are mild.
Publish Date	2025-11-21 03:54
Citation	<p>Mori K, Kamijo Y, Doi T, Abe H, Takeuchi I. Severe venlafaxine poisoning successfully rescued with veno-arterial extracorporeal membrane oxygenation: A case report. <i>World J Clin Cases</i> 2025; 13(33): 113560</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i33/113560.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i33.113560

Full Article (PDF)	WJCC-13-113560-with-cover.pdf
CARE Checklist–2016	113560-CARE-Checklist-2016.pdf
Manuscript File	113560_Auto_Edited_021831.docx
Answering Reviewers	113560-answering-reviewers.pdf
Audio Core Tip	113560-audio.m4a
Conflict-of-Interest Disclosure Form	113560-conflict-of-interest-statement.pdf
Copyright License Agreement	113560-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s)	113560-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	113560-non-native-speakers.pdf
Peer-review Report	113560-peer-reviews.pdf
Scientific Misconduct Check	113560-scientific-misconduct-check.png
Scientific Editor Work List	113560-scientific-editor-work-list.pdf
CrossCheck Report	113560-crosscheck-report.pdf