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Articles Published Processes
2/28/2026 8:32:55 AM | Browse: 1 | Download: 0
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Received |
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2025-08-29 08:54 |
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Peer-Review Started |
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2025-08-29 08:54 |
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First Decision by Editorial Office Director |
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2025-10-17 06:51 |
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Return for Revision |
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2025-10-17 06:51 |
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Revised |
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2025-10-26 20:42 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-24 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-24 02:58 |
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Articles in Press |
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2025-12-24 02:58 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-12 08:05 |
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Publish the Manuscript Online |
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2026-02-28 08:32 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Efficacy of hyperbaric oxygen therapy in the treatment of depression
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Marya Ahsan, Saif Ahmed, Riyaz Ahamed Shaik, Mohammed Shakil Ahmad, Khulud Mahmood Nurani and Prashanth A |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Khulud Mahmood Nurani, MD, School of Medicine, University of Nairobi, Mbagathi Road, PO Box 30197-00100, Kenya. khuludnurani@gmail.com |
| Key Words |
Hyperbaric oxygen therapy; Depression; Systematic review; Cognitive function; Functional outcomes; Therapeutic efficacy |
| Core Tip |
This systematic review synthesizes evidence from six randomized controlled trials evaluating hyperbaric oxygen therapy (HBOT) as an adjunct or stand-alone treatment for depression, including treatment-resistant and comorbid presentations. Across diverse populations, HBOT consistently reduced depressive symptom scores, improved cognition, functional independence, sleep quality, and cerebral perfusion, and in some studies accelerated response when combined with antidepressants. These findings position HBOT as a biologically plausible, multimodal neuromodulatory strategy for mood disorders that extends beyond symptom relief to neurocognitive recovery and functional restoration. |
| Publish Date |
2026-02-28 08:32 |
| Citation |
Ahsan M, Ahmed S, Shaik RA, Ahmad MS, Nurani KM, A P. Efficacy of hyperbaric oxygen therapy in the treatment of depression. World J Psychiatry 2026; 16(3): 113572 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i3/113572.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i3.113572 |
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