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Articles Published Processes
3/30/2015 5:46:00 PM | Browse: 1201 | Download: 1607
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Received |
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2014-05-17 11:42 |
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Peer-Review Started |
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2014-05-17 20:14 |
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To Make the First Decision |
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2014-06-10 13:30 |
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Return for Revision |
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2014-06-11 10:24 |
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Revised |
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2014-06-23 00:00 |
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Second Decision |
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2014-07-30 10:08 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-07-30 10:24 |
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Articles in Press |
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2014-07-30 10:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-08-25 23:47 |
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Typeset the Manuscript |
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2015-03-13 16:13 |
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Publish the Manuscript Online |
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2015-03-30 14:23 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Effects of neutrophil elastase inhibitor in patients undergoing esophagectomy: A systematic review and meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Qiang Wang, Long-Qi Chen, Yong Yuan, Wen-Ping Wang, Zhong-Xi Niu, Yu-Shang Yang and Jie Cai |
| Funding Agency and Grant Number |
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| Corresponding Author |
Long-Qi Chen, Professor, Department of Thoracic Surgery, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu 610041, Sichuan Province, China. drchenlq@gmail.com |
| Key Words |
Neutrophil elastase inhibitor; Esophageal cancer; Esophagectomy; Systematic review; Meta-analysis |
| Core Tip |
Radical esophagectomy has been adopted in patients with esophageal carcinoma to improve survival. This technique is highly invasive, leading to excess surgical stress, a perioperative mortality of 3%-10%, and pulmonary disorders account for nearly 30%-60%. Sivelestat sodium hydrate, a specific neutrophil elastase inhibitor, actively protects patients with acute respiratory diseases. The efficacy and safety of sivelestat administered during esophagectomy has produced conflicting results and the conclusions from relevant studies are presented. This meta-analysis revealed that sivelestat is beneficial in patients undergoing esophagectomy, especially in terms of the duration of mechanical ventilation and the incidence of pulmonary complications. |
| Publish Date |
2015-03-30 14:23 |
| Citation |
Wang ZQ, Chen LQ, Yuan Y, Wang WP, Niu ZX, Yang YS, Cai J. Effects of neutrophil elastase inhibitor in patients undergoing esophagectomy: A systematic review and meta-analysis. World J Gastroenterol 2015; 21(12): 3720-3730 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i12/3720.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i12.3720 |
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