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3/14/2026 4:49:28 AM | Browse: 1 | Download: 0
Publication Name World Journal of Nephrology
Manuscript ID 113599
Country United States
Received
2025-08-29 05:09
Peer-Review Started
2025-08-29 05:09
First Decision by Editorial Office Director
2025-10-13 08:52
Return for Revision
2025-10-13 08:52
Revised
2025-10-27 17:23
Publication Fee Transferred
Second Decision by Editor
2026-01-07 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-07 11:13
Articles in Press
2026-01-07 11:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-11 02:09
Publish the Manuscript Online
2026-03-14 04:49
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Health Care Sciences & Services
Manuscript Type Retrospective Cohort Study
Article Title Long-term patiromer adherence and renin-angiotensin aldosterone system inhibitor utilization: A retrospective study
Manuscript Source Invited Manuscript
All Author List Nathan Kleinman, Tejas Desai and Charuhas Thakar
ORCID
Author(s) ORCID Number
Nathan Kleinman http://orcid.org/0000-0001-5779-3679
Funding Agency and Grant Number
Corresponding Author Nathan Kleinman, PhD, Department of Data Analysis and Research, Kleinman Analytic Solutions, LLC., 405 Cool Valley Dr., Paso Robles, CA 93446, United States. nathan@kleinmansolutions.com
Key Words Renin-angiotensin aldosterone system inhibitors; Patiromer; Adherence; Hyperkalemia; Proportion of days covered
Core Tip Increased use and optimal dosing of guideline-recommended renin-angiotensin aldosterone system inhibitors (RAASi) improve patient outcomes in patients with heart failure, chronic kidney disease, and diabetes. However, RAASi use is also associated with increased occurrence of high potassium levels (hyperkalemia). Patiromer is indicated for the treatment of hyperkalemia, and patients taking patiromer are better able to tolerate optimal doses of RAASi than patients not taking patiromer. In this United States study from 2014 to 2019, 3323 patients who were more adherent with patiromer proportion of days covered > 80% used more RAASi than 10124 patients who were less adherent with patiromer (proportion of days covered ≤ 80%).
Publish Date 2026-03-14 04:49
Citation

Kleinman N, Desai T, Thakar C. Long-term patiromer adherence and renin-angiotensin aldosterone system inhibitor utilization: A retrospective study. World J Nephrol 2026; 15(1): 113599

URL https://www.wjgnet.com/2220-6124/full/v15/i1/113599.htm
DOI https://dx.doi.org/10.5527/wjn.v15.i1.113599
Full Article (PDF) WJN-15-113599-with-cover.pdf
STROBE Statement 113599-STROBE-statement.pdf
Manuscript File 113599_Auto_Edited_075731.docx
Answering Reviewers 113599-answering-reviewers.pdf
Audio Core Tip 113599-audio.m4a
Biostatistics Review Certificate 113599-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113599-conflict-of-interest-statement.pdf
Copyright License Agreement 113599-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113599-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113599-institutional-review-board-statement.pdf
Peer-review Report 113599-peer-reviews.pdf
Scientific Misconduct Check 113599-scientific-misconduct-check.png
Scientific Editor Work List 113599-scientific-editor-work-list.pdf
CrossCheck Report 113599-crosscheck-report.pdf