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12/10/2025 7:48:07 AM | Browse: 4 | Download: 1
Publication Name World Journal of Gastroenterology
Manuscript ID 113608
Country China
Received
2025-08-29 09:13
Peer-Review Started
2025-08-29 09:13
First Decision by Editorial Office Director
2025-09-09 10:27
Return for Revision
2025-09-09 10:27
Revised
2025-09-23 10:00
Publication Fee Transferred
2025-09-26 09:56
Second Decision by Editor
2025-10-31 02:32
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-31 10:12
Articles in Press
2025-10-31 10:12
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-04 08:50
Publish the Manuscript Online
2025-12-10 07:48
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Epidemiology of metabolic dysfunction-associated steatotic liver disease/metabolic dysfunction-associated steatohepatitis and associated cardiometabolic factors in adults in China (2013-2023): A systematic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Shang-Yu Chai, Ru-Ya Zhang, Gail Fernandes, Yi-Man Zheng and Lai Wei
ORCID
Author(s) ORCID Number
Shang-Yu Chai http://orcid.org/0009-0003-6644-3277
Lai Wei http://orcid.org/0000-0003-2326-1257
Funding Agency and Grant Number
Funding Agency Grant Number
MSD China
Corresponding Author Lai Wei, MD, PhD, Hepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, Tsinghua University, No. 168 Litang Road, Changping District, Beijing 102218, China. weilai@mail.tsinghua.edu.cn
Key Words Metabolic dysfunction-associated steatohepatitis; Metabolic dysfunction-associated steatotic liver disease; Epidemiology; Disease burden; Meta-analysis
Core Tip According to our analysis, the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) was 30.4% [95% confidence interval (CI): 29.4-31.3] during the study period in China, and its prevalence is increasing over time. Several prevalent extrahepatic comorbidities of MASLD were identified. Meanwhile, the prevalence rates of MASLD in individuals with dyslipidemia, obesity, and hypertension were 59.9% (95%CI: 52.6-67.0), 53.9% (95%CI: 47.9-59.9), and 44.3% (95%CI: 41.1-47.6), respectively. Furthermore, the prevalence of lean MASLD (body mass index < 24 kg/m2), which is usually ignored in clinical practice, was 12.0% (95%CI: 10.0-14.0), with 21.7% of the total MASLD population in China having lean MASLD. Additionally, several single-nucleotide polymorphisms were linked to the risk of MASLD.
Publish Date 2025-12-10 07:48
Citation

Chai SY, Zhang RY, Fernandes G, Zheng YM, Wei L. Epidemiology of metabolic dysfunction-associated steatotic liver disease/metabolic dysfunction-associated steatohepatitis and associated cardiometabolic factors in adults in China (2013-2023): A systematic review and meta-analysis. World J Gastroenterol 2025; 31(46): 113608

URL https://www.wjgnet.com/1007-9327/full/v31/i46/113608.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i46.113608
Full Article (PDF) WJG-31-113608-with-cover.pdf
PRISMA 2009 Checklist 113608-PRISMA-2009-Checklist.pdf
Manuscript File 113608_Auto_Edited_012926.docx
Answering Reviewers 113608-answering-reviewers.pdf
Audio Core Tip 113608-audio.m4a
Biostatistics Review Certificate 113608-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113608-conflict-of-interest-statement.pdf
Copyright License Agreement 113608-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 113608-non-native-speakers.pdf
Supplementary Material 113608-supplementary-material.pdf
Peer-review Report 113608-peer-reviews.pdf
Scientific Misconduct Check 113608-scientific-misconduct-check.png
Scientific Editor Work List 113608-scientific-editor-work-list.pdf
CrossCheck Report 113608-crosscheck-report.pdf