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11/28/2025 3:10:37 AM | Browse: 18 | Download: 57
Publication Name World Journal of Gastroenterology
Manuscript ID 113650
Country China
Received
2025-09-01 08:36
Peer-Review Started
2025-09-01 08:36
First Decision by Editorial Office Director
2025-09-28 10:50
Return for Revision
2025-09-28 10:50
Revised
2025-10-10 11:02
Publication Fee Transferred
2025-10-13 09:16
Second Decision by Editor
2025-10-27 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-27 03:15
Articles in Press
2025-10-27 03:15
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-21 07:12
Publish the Manuscript Online
2025-11-28 03:10
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Randomized Controlled Trial
Article Title Covering the biopsy hole check valve with “enzymolysis gauze” reduces bacterial contamination in the endoscopy room
Manuscript Source Unsolicited Manuscript
All Author List Hu-Bin Xia, Ying-Dong Hou, Yuan Zhang, Ai-Yu Yu, Qi Ding, Wen-Li Ruan, Yi-Shen Mao, Shu-Jiong Feng, Cong Ding and Yi-Feng Zhou
ORCID
Author(s) ORCID Number
Shu-Jiong Feng http://orcid.org/0009-0006-7887-8632
Yi-Feng Zhou http://orcid.org/0009-0000-8346-0122
Funding Agency and Grant Number
Funding Agency Grant Number
Construction Fund of Key Medical Disciplines of Hangzhou 2025HZGF05
Key R&D Program of Zhejiang Province No. 2023C03054, No. 2024C03048
Key Discipline of lntegrated Chinese and Western Medicine (Digestive Diseases) in Zhejiang Province 2024-XK-61
Zhejiang Province Medical and Health Science and Technology Plan Project 2021KY848
Corresponding Author Yi-Feng Zhou, Chief, MD, Department of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, No. 261 Huansha Road, Shangcheng District, Hangzhou 310000, Zhejiang Province, China. zhouyifeng@hospital.westlake.edu.cn
Key Words Bacterial contamination; Aerosol; Enteric bacterial microflora; Colonoscope; Endoscopy; Enzymolysis gauze; Biopsy hole check valve; Infection
Core Tip Endoscopy-related infections are underestimated due to difficulties in diagnosis, misdiagnosis, and underreporting. Bacterial contamination during colonoscopy poses a significant challenge, yet limited research has focused on bacterial aerosols, particularly those originating from the biopsy valve. This study introduces a simple yet effective approach to mitigate bacterial aerosol contamination in the endoscopy room. Our findings demonstrate that covering the biopsy valve with an enzymolysis gauze during colonoscopy significantly reduces airborne bacterial aerosols. This could improve safety for both patients and healthcare personnel.
Publish Date 2025-11-28 03:10
Citation

Xia HB, Hou YD, Zhang Y, Yu AY, Ding Q, Ruan WL, Mao YS, Feng SJ, Ding C, Zhou YF. Covering the biopsy hole check valve with “enzymolysis gauze” reduces bacterial contamination in the endoscopy room. World J Gastroenterol 2025; 31(44): 113650

URL https://www.wjgnet.com/1007-9327/full/v31/i44/113650.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i44.113650
Full Article (PDF) WJG-31-113650-with-cover.pdf
CONSORT 2010 Statement 113650-CONSORT-2010-statement.pdf
Manuscript File 113650_Auto_Edited_031147.docx
Answering Reviewers 113650-answering-reviewers.pdf
Audio Core Tip 113650-audio.m4a
Biostatistics Review Certificate 113650-biostatistics-statement.pdf
Clinical Trial Registration Statement 113650-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 113650-conflict-of-interest-statement.pdf
Copyright License Agreement 113650-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 113650-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 113650-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113650-non-native-speakers.pdf
Peer-review Report 113650-peer-reviews.pdf
Scientific Misconduct Check 113650-scientific-misconduct-check.png
Scientific Editor Work List 113650-scientific-editor-work-list.pdf
CrossCheck Report 113650-crosscheck-report.pdf