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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 113681
Country China
Received
2025-09-07 14:58
Peer-Review Started
2025-09-07 14:59
First Decision by Editorial Office Director
2025-10-11 07:07
Return for Revision
2025-10-11 08:17
Revised
2025-10-22 20:27
Publication Fee Transferred
2025-10-24 09:20
Second Decision by Editor
2025-11-17 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-17 23:52
Articles in Press
2025-11-17 23:52
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-04 02:09
Publish the Manuscript Online
2026-01-12 10:07
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Hepatic artery infusion chemotherapy for advanced hepatocellular carcinoma with obstructive jaundice: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Li Zhang, Pan Xiao, Lian-Dong Shi, Ke-Xin Chen and You-Fu Bing
ORCID
Author(s) ORCID Number
Pan Xiao http://orcid.org/0009-0009-5523-9418
Funding Agency and Grant Number
Corresponding Author Pan Xiao, Research Fellow, Researcher, Department of Minimally Invasive Interventional Radiology, Guilin People’s Hospital, No. 12 Wenming Road, Xiangshan District, Guilin 541000, Guangxi Zhuang Autonomous Region, China. xp13807836988@163.com
Key Words Hepatocellular carcinoma; Obstructive jaundice; Hepatic artery perfusion chemotherapy; Portal vein tumor thrombosis; Case report
Core Tip Hepatocellular carcinoma with portal vein tumor thrombosis (PVTT) and obstructive jaundice is rare and generally carries a poor prognosis. In this case, hepatic artery infusion chemotherapy (HAIC) followed by targeted immunotherapy achieved significant tumor shrinkage, improved bilirubin levels, and regression of PVTT. The patient attained 20 months of progression-free survival and 29 months of overall survival, indicating that HAIC conversion therapy followed by targeted immunotherapy may provide an effective option when biliary drainage is not feasible.
Publish Date 2026-01-12 10:07
Citation

Zhang L, Xiao P, Shi LD, Chen KX, Bing YF. Hepatic artery infusion chemotherapy for advanced hepatocellular carcinoma with obstructive jaundice: A case report and review of literature. World J Gastrointest Oncol 2026; 18(1): 113681

URL https://www.wjgnet.com/1948-5204/full/v18/i1/113681.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i1.113681
Full Article (PDF) WJGO-18-113681-with-cover.pdf
CARE Checklist–2016 113681-CARE-Checklist-2016.pdf
Manuscript File 113681_Auto_Edited_064641.docx
Answering Reviewers 113681-answering-reviewers.pdf
Audio Core Tip 113681-audio.wav
Conflict-of-Interest Disclosure Form 113681-conflict-of-interest-statement.pdf
Copyright License Agreement 113681-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 113681-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 113681-non-native-speakers.pdf
Peer-review Report 113681-peer-reviews.pdf
Scientific Misconduct Check 113681-scientific-misconduct-check.png
Scientific Editor Work List 113681-scientific-editor-work-list.pdf
CrossCheck Report 113681-crosscheck-report.pdf